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Ne0
18-07-2009, 23:49
I would say 20% is significant. However, I don't believe in chasing a high with a maintenance drug, whether you take it daily (give up, will you) or just recreationally. Someone else is just going to screw up and die and I won't have my medicine.


Yeah and you also don't believe chasing a high with pain killers (any opiate), ADHD/ADD medicines (all amphetamines and methyphenidate), anxiety and panic attack medicines (benzos)? Oh and also cannabis is used as painreliever so you shouldn't smoke that recreationally either.

Buprenorphine is as good to use recreationally as any other opiate would be. Also as far I know it's hard to kill yourself with buprenorphine (as far you don't take any other depressants).

Dr Pepper
14-03-2010, 21:56
Hey, got a couple free 8mg suboxones. Been bangin a bit of h recently (past month or so, 2-3 days in between uses, and havent felt any physical withdrawls from stopping, so i dont think my usage got out of control. Main symptom has been an urge to use, and maybe slight difficulty sleeping (easily remedied by some trazadone that was given to me) My last dose was not much, maybe 40mg worth of an oxy-equivalent dose (of heroin) plugged about 19-20 hours ago (barely got me high), to give you an idea of my tolerance.
Been reading up on suboxone and am just about to plug about 1mg-1.3 mg worth (cuts weren't exact). I'll update once i'm (hopefully) high as hell, and will use different methods of administration (sublingual/snorted) in the days to follow to asses which works best for me in terms of recreational value. I got my money on plugged. Not gonna bang, as any reminiscent markings due to my recent iv use has vanished, and am currently at parents' house for the beginning of spring break. Dont want to arouse any suspicion. And sorry for reviving an old thread, just thought i'd contribute some useful comparisons for anybody that could use the anecdotal info.
--Dr Pepper
Edit: **** my rectal admins have gotten sloppy, i bet a good 1/8-1/4 of solution (i hope, doubt it was any more. ) came out. So prob still got almost 1mg in there. Never had this prob before, I need to stand on my head against a wall like i used to when utilizing this ROA haha. Let gravity do the work, w.o taking any chances. Sorry for the imagery. Do ya'll other pluggers withdrawl the syringe immediately after plugging, or leave it in for a bit to let shit settle(no pun intended). It seems when i take it out right after pushing the plunger is when i tend to experience a loss of my solution via leakage. And to tighten or not to tighten (as in hold your ass closed) before taking out syringe? It seems like doing so may have created pressure that caused leakage when syringe came out.

So that didnt pan out as i expected, feeling a little opiated but either i lost too much or am used to full agonists.
Just snorted a .5 on top of the plugged .5-1mg, nothing yet. Gonna go smoke a stoge as that generally causes me to nod when im on other opiates.

Captain.Heroin
15-03-2010, 01:10
So that didnt pan out as i expected, feeling a little opiated but either i lost too much or am used to full agonists.
Just snorted a .5 on top of the plugged .5-1mg, nothing yet. Gonna go smoke a stoge as that generally causes me to nod when im on other opiates.
Your heroin use might have rendered your dose less euphoric than you planned.

Give it a few days and your doses should get you feeling better. :) - you can still utilize buprenorphine to help avoid WD symptoms in the mean time.

Good luck trying out the different ROA's.

jaguraguguru
15-03-2010, 05:17
Thanks for all the suggestions for this ROA, which I have not yet utilized. I have an exceptionally low tolerance for bupe (though a pretty high natural tolerance for full mu-agonists, fuck me) and I am currently out, so after a week's break or so, a nice plugged dose should send me to la-la land %) Been too long since I've been really HIGH on the shit though.

On a related topic, from those of you that have experienced this, how long in general does bupe significantly antagonize the effects of full agonists? I know the half-life is 32 hours and I can do math, I'm just asking for anecdotal evidence for its actual significance. Of course it depends what dose of both you're taking, but consider your normal maintenance dose of bupe. If you took your bupe yesterday but then took what you would consider a medium-high dose of full agonist (accounting for reduction in tolerance from using bupe and not a full agonist). How much reduced would the experience be? I have taken 30mg oxy one day after taking suboxone, after having used it daily for many months (recreationally/therapeutically) and gotten only buzzed, even with alcohol and xanax. A nice fat bag of H intranasal got me really heavily stoned for about an hour, but not too much euphoria. Would their effects be greatly increased with another day or two in between or is it usually only a slight difference? Thanks and be excellent to eachother (and yourself!) :)

-Jaguraguguru

funkee
15-03-2010, 06:46
I plugged it for more than a year, because I couldn't take the taste of high doses of Suboxone. It works fine but do it after clearing your bowels, or it will make you go shortly thereafter and you'll end up losing it. +T 3:00 to +T 8:00 you may have some GI disturbances including gas. Take some anti-gas (simethicone) to help with that. The trouble with gas is that you might accidentally go in your pants trying to fart it out. And holding in your farts for a long time is quite uncomfortable. The gas goes away eventually as all the water gets absorbed. I prefer to get it out before going to bed. After taking it orally for a while, plugging the same dose gave me a nice buzz. After plugging it for a long while, taking it orally gave me a small buzz. It lost its magic rather quickly. I'm so thankful for the generic sub.

jaguraguru Bupe's blockade effect depends on the dose and the duration. Bupe binds to proteins and is slowly released over a period of time. A small dose (<2mg for less than week) ought to clear out within 48 hours for 90% full agonist effect. It may take 72 hours to clear out. For high doses 24-32mg for many months, may take 5-7 days to clear out of your system.

Jman1984
01-04-2010, 21:36
Just so people don't have to go crazy looking threw this thread like i did.

The suboxone pluging tech. Is it dangerous?

I just lube up a doctor glove take a whole 8mg pill and jam it up with index finger. being very delicate tho sence it citrisness would probably hurt if i cut anything. No worry about water drippin out my ass like most with syringes. just pop it in far enough and poof its gone. and i feel great way better then oral. plus that god damn taste yuk.

Will it harm my insides? idk but would like to cuz i vow to never taste one again

Captain.Heroin
02-04-2010, 07:03
Just so people don't have to go crazy looking threw this thread like i did.

The suboxone pluging tech. Is it dangerous?

I just lube up a doctor glove take a whole 8mg pill and jam it up with index finger. being very delicate tho sence it citrisness would probably hurt if i cut anything. No worry about water drippin out my ass like most with syringes. just pop it in far enough and poof its gone. and i feel great way better then oral. plus that god damn taste yuk.

Will it harm my insides? idk but would like to cuz i vow to never taste one again

You should dissolve the Suboxone in water, and plug that instead. 8mg is an entirely too high of a dose for plugging. I theorize not all of it is dissolving, or it's at least taking much longer to dissolve.

No, it's not dangerous.

DexterMeth
02-04-2010, 07:16
I haven't done this with subs, but I saw some people saying it was way too thick with how much water they use...1, you don't need nearly as much bupe as you normally do for sublingual, and 2,,.fucking filter it through cotton a few times first.

morphinanymous
02-04-2010, 07:32
I have only plugged subs using a baby syringe with water, after filtering with a 32 gauge riggeroo forever. I was using h up until the day before 2.5 buns/ 2 grams of good high purity at that point daily and my last shot was about 18 hours before. It was a 32mg plug..it did nothing but jack me up a little bit and keep me from having a seizure. I have an enormous tolerance for bupe or opiates in general. I didn't like it and I would never stick anything I hadn't turned into liquid in my ass, ever, even though those baby plugs feel like dropping your soap in prison, fuck.

Jman1984
02-04-2010, 16:33
You should dissolve the Suboxone in water, and plug that instead. 8mg is an entirely too high of a dose for plugging. I theorize not all of it is dissolving, or it's at least taking much longer to dissolve.

No, it's not dangerous.

Well im on my second week of pluggin a whole 8mg pill. the whole thing dose desolve within a half hour. with no leakage like a syringe. Just plug and go. Only problems ive run across is you gotta have a clean bowl first or you will shit out water in about 30 mins. I think stickin one whole pill up my ass is alot better that taking 32mg daily by mouth. Just don't really see how ppl can throw 1mg in water and be good for the day. sound to me like you really dont need subs at all...

ThePharmicist
07-04-2010, 07:24
Well, here I am, laying on the bathroom floor. Just plugged .5mg of bupe (I take 4mgs a day) and I must say, damn, not bad. T+15 or so and my dose feels much warmer than it usually does. I'm fairly happy with this ROA so far. I may even plug another .5mg before bed. The only downside to this is having something go in your ass and *ahem* release itself there. I swear to god I felt it in my stomach. Much respect to my girlfriend now, much respect. Haha

I suppose it's about T+20 now. I'll post back after full effects are reached.


Just tried another .5mgs roughly one hour prior to the first dose, I can say that this time there was a definite rush and it felt pretty good - about as good as you can get with Suboxone. That being said, it's unfortunate that Suboxone is only a partial agonist. I apologize for rambling but I got into a discussion with my Sub Doc/Psychiatrist the other day. Last week I completely relapsed and was back on OC's for the whole week. It had been about a year since I've felt the wonderful euphoria from opiates. I was talking to my doc about it, and we were discussing why I don't have the RIGHT as a human being to feel as good as I want to feel, whenever I want to feel that way. If I'm happy and content using OC's, who's business is it to stop me? The main consequences that come from opiate use are more related to the time one has to spend obtaining it, and the money they have to spend obtaining it. If it was easily accessible and cheap, I don't see what the problem would be. I feel I should have the right to pursue happiness in my life whichever way I see fit, as long as it doesn't hurt other people (psychically or monetarily - emotional is another story).

Ugh, why can't opiates be OTC? I just want to be HAPPY. . .

BearLeeLive
10-04-2010, 04:02
^ If you take suboxone as directed, the precipitated withdrawals should be so mild that you barely notice them.

Thats why I dont understand how some p eople feel like death for hour after hour. Ive never had it happen to me like that.

im the same for the most part. th only time i was sick for hours after taking subs via SL it was a 2mg tab and i was kicking a 40mgs a shot of hydromorphone.
the only time i had precipitated w/d was in hospiAL DTOX and it only lasted abou 15 to 30 mins
;)

jaguraguguru
11-04-2010, 21:33
Well I just plugged a pretty normal dose for me that would normally get me buzzed but probably not too high, with a rather low dose of adderall, I'll let you guys know how it works out for me. Actually I'm definitely starting to feel something now, less than 5 min post-plug, so I'd say it certainly does work very quickly. Hopefully I can feel the subs through the adderall well enough to gauge its strength.

Well overall, I'd say that i only got slightly more buzzed than I'd have expected to if i'd snorted that dose as I normally do but it certainly came on much, much faster, being fully evident within 20 minutes for sure, rather than the 1 hour it usually takes for snorting. Also, the adderall was actually far, far more pleasant than oral or nasal ingestion and has given me quite a nice boost to the whole day. It's definitely possible that the amphetamine is masking the effects of the bupe to some extent as when I think about the effects, the bupe does seem rather strong, but somehow hindered. I'll probably try a redose with about 1/2 - 2/3 the original dose of bupe without any more amphetamine (maybe a little :)) in a little while and if so, I will post my results again.

Anyone else with experience, particularly those new to it or who haven't posted, to share on this ROA for bupe?

Bojangles69
05-06-2010, 19:29
I tried this the other day to stretch my dose and I was AMAZED how well pluggin works and some of the effects I got from the bupe. I had only plugged like .5mg too and it absolutely destroy taking .5mg sublingually.

I'm amazed by how little I had plugged and how much stronger it felt. I wanted to stretch my bupe so today I tried the sublingual alcohol method. I'm not a fan of it and did it exactly as stated. I brushed the crap out of my mouth, used mouth wash, and used 100 proof smirnoff as the carrier. It felt no different than taking it under my tounge and I believe because when you hold it under your tounge long enough the same amount of bupe will absorb no matter what liquids its in.

Yes alcohol permeates faster but alcohol also causes excess salivation, which in turn pushes the bupe BACK INTO your mouth from your salivary glands.
Your not increasing the BA because its the same exact ROA. And even though the alcohol absorbs quicker, water still dissolves it fully and it doesn't trigger your salivary glands to push the bupe back out.

So obviously I'm only left with pluggin. I can get 4 times the amount of bupe roughly by pluggin. But I have a problem using syringes as they are honestly "too big", I was in a world of pain just trying to put a tiny needless syringe up there. I considered the idea of a straw, but theres no way to pump it out.
I need something tiny enough that can pump liquid out, so I was thinking of using an eye dropper. But my question is what do you pluggers usually use to do it? I can't understand why it hurts so bad to push a syringe up there. It justs too much pressure it seems. I was getting it like 2 inches in at points and because it was so tight it would slide right out from the pressure. It prob took about a good half hour to do just 1 plug successfully, but I don't have the courage to plug the same way I did.
Is there any guaranteed painless ways of pluggin? I just wish I could make this procedure somewhat comfortable.

Oh ROXIanne!
05-06-2010, 19:57
mabey you could use a tiny funnle

Bojangles69
05-06-2010, 20:08
Thats interesting but I think I'd have to keep my ass in the air and some how pour the bupe into it which would be hard.
Right now I have a syringe WITH the needle on. I took a cu-tip that you use to clean your ears and cut the 2 cotton wads off each end. I'm trying to figure out how to afix the tube onto the needle so it fits tight enough.
That way I can just stick the cu tip up there, and try squeezing the plunger to see if it'll go all the way up the cu tip and into my rear. The problem is for some reason these cu tips aren't hollow (like a lot are) so I'm looking around my house for other things. I have some fishline tubing too thats relatively thin and I may be able to hot glue it into the syringe. Still playing around with stuff.

Ok I found something that works perfectly. I found an old bottle of windex and cut the tube off the spray head. I washed the tube out with scolding hot water to get all the windex out.

If you take the pin off any syringe theres a tiny little plastic piece on the mouth of the syringe that the pin slides over. Believe it or not the tube from the windex fits PERFECTLY over that tube. I cut off about 4 inches of the tube and heated it with a lighter just so it gets soft, then I pressure fitted it over the mouth. It slides on then hardens like it was made for the syringe water tight and all.

Its MUCH easier to get up there, and as long as you leave a little air in the tube you need that extra space to push it all out the windex tube, but it works perfectly. You can barely feel it going in and you can get in 3-4 inches w/out feeling uncomfortable. For anyone with really tight rear areas like me you def want to try this out as it works 100times better. The problem is you don't wanna really throw the syringe away or you have to make a new one. I rinsed the tube in alcohol and washed it down than will save for reuse. Another thing I like is you don't have to lay on your side. Once its in just don't fart and you're good to go. This also actually saves time because rather then holding a liquid in your mouth for 20 minutes it push and go.
I'll take pictures of the device I made so people understand better how well it works. Oh and if you're considering doing this before I get pics up remember you must also heat the end thats going in your butt. If you cut the tube with scissors like I did TRUST ME when I say those sharp edges will feel like they're ripping your ass as it goes in. All I did was heat the tip till it rounded off, and when I went in the second time it was smooth as could be.

hydrobliss
05-06-2010, 21:46
I use a small needless syringe that I got at the hospital.

I dont shove it all the way in my ass tho.. I simply get the small tip into my sphingter and hit the plunger.. it goes in just fine and with no violation to my asshole.

and yes.. plugging bupe is amazing

Captain.Heroin
05-06-2010, 22:57
Looks like your problem is solved! Congratulations.

I'm going to merge this in the pre-existing rectal buprenorphine thread, because this fits well over there.

Bojangles69
06-06-2010, 07:46
Thank you its incredible how long you can make bupe last doing it this way. Extremely efficient and strong. I will have to switch back to sublin soon though to taper. Captain Heroin how long before you think the body "adapts" to bupe (wds). And what dose do you recommend jumping off of? Thanks.

Captain.Heroin
06-06-2010, 07:50
Thank you its incredible how long you can make bupe last doing it this way. Extremely efficient and strong. I will have to switch back to sublin soon though to taper. Captain Heroin how long before you think the body "adapts" to bupe (wds). And what dose do you recommend jumping off of? Thanks.

How long until you adapt to buprenorphine withdrawal - I have heard various things, I haven't personally quit buprenorphine yet but I would guess 1-3 weeks at the longest, possibly earlier.

I think it is key to jump off of a dose that's < 0.5mg or so. If you can do every other day dosing that would help too.

Good luck!

KnowBudz
06-06-2010, 22:10
Acute withdrawal symptoms from buprenorphine aren't too terrible (though it is certainly unpleasant) What kills me is the PAWS; which for me means persistent insomnia; weird and seemingly unrelated physical complaints; and difficulty thinking clearly Supposedly; buprenorphine maintenance can facilitate positive changes in brain chemistry Everyone is different of course

Someone had asked earlier about how long it takes for buprenorphine to completely clear your system: I had read an article a few weeks ago about this so I checked it again Apparently; burprenorphine and its metabolites are detectable for a range of 9-14 days; with a median among the test subjects of 11 days

subutxfame
01-07-2010, 10:12
its amazing how many of us have actually leeaned toward this roa!! i love plugging and wouldnt have it anyother way!walking around with that nasty crap in my mouth for 10 minutes was horrible! i dont disolve or anything. simply use ky-gelly,one drop on the pill for lube and dissolving later with body temp!! its painless and awesome! the only thing is-i plug 8mgs at a time-the same amount i was prescribed daily.. 3-8mgs subling. but i am also on subutex--the suboxone migraines were no joke and no med-NO med!!!would get rid of it. my doc said it was the naloxone in the suboxone. the whole idea that the nalox isnt absorbed is bs!! google suboxone headaches and see for yourself. im for pluggin the subs and may try snortin.anyone have any expierience with this??

Madmike
03-07-2010, 11:52
I just cannot seem to get it working right. When I pull the syringe out of my anus, the reflex pushes the syringe and the content of the anal cavity out.
It sucks I wasted 1 mg of bupe last night that way.

axe battler
13-07-2010, 23:57
just tried 4mg 15 minutes ago; very nice! no syringe, just lubed my finger up and stuck it up there good and deep: delightful!

sp0r
16-07-2010, 03:04
For the guy who it shot back out of his ass it is probably because you are constipated. And about the suboxone headaches HELL YES!@ I get horrible migraine headaches from suboxone and NONE from subutex. I was on subutex for years because I told my doctor about the headache and he recently switched me back to suboxone saying that it is BS that the naloxone doesnt do anything to cause headaches. My opinion is that since subutex went generic Reckitt/Bensicker is pushing the doctors to prescribe more suboxone.. Its all about the $$ for these doctors. While they may be helping with one disease of addiction they can care less that they are increasing my already attrocious migraine headaches. Its bullshit.

Paulination
26-08-2010, 08:55
Hey I dissolved a lot of my pills in a saline nose spray and I read that saline solution is good for rectal use because of its retention do u think it wuld be ok?

jamesBrown
27-08-2010, 03:29
Just in case anybody gets SUPER FUCKING CONSTIPATED like I do from there suboxone(crap only once or twice a week), I have found a solution....finally!!

I had tried taking SHITLOADS of laxatives and that pretty much did NOTHING for my constipation so I didnt know what to do.

For som reason I decided to try that Activia yogurt shit(I guess I saw so many of the goddamn commercials it finally got to me)....and HOORAY....it worked like a charm....who would of thought?

It says to give it two weeks to "regulate" your digestive system but I noticed it working within 3 days, and by one week I was crapping almost every day!!....I couldnt fucking believe it...after months of extreme constipation, a simple yogurt product was the answer!

Well, anyway...I hope my experience helps others with there constipation issues because out of all the opiates ive taken, suboxone is BY FAR the worst when it comes to "blocking the exit".

8L4YN3
01-09-2010, 17:37
Why am i reading about people using like 6mg of bupe sublingually to get off, when im on 24mg a day and i still wake up feeling mildly crap?

Makes no sense, i wasnt even an IV H user for over a month, i guess it dosn't take long... 500mg oxycodone isnt even a substantial amount anymore? That used to be a fucking good stash now its not even a nod(this was just before i got on suboxone).............

I dunno i've just always thought it took months to years to develop a tolerance where one could dose 500mg of oxycodone and not even nod...

Or can natural tolerance play a role, ive always handled by opies better than any of my mates but this is just insanity...


Also reading about the plugging roa, once i get to the point in my program where i get 4 take home doses per week im def gunna be trying this method... fuck lol

jamesBrown
01-09-2010, 18:30
Why am i reading about people using like 6mg of bupe sublingually to get off, when im on 24mg a day and i still wake up feeling mildly crap?

Makes no sense, i wasnt even an IV H user for over a month, i guess it dosn't take long... 500mg oxycodone isnt even a substantial amount anymore? That used to be a fucking good stash now its not even a nod(this was just before i got on suboxone).............

I dunno i've just always thought it took months to years to develop a tolerance where one could dose 500mg of oxycodone and not even nod...

Or can natural tolerance play a role, ive always handled by opies better than any of my mates but this is just insanity...


Also reading about the plugging roa, once i get to the point in my program where i get 4 take home doses per week im def gunna be trying this method... fuck lol

No, its very common to develope a HUGE tolerance for opiates very quickly when you are taking them all the time. When your an addict, there never seems to be enough opiates to take.

And I dont know how to explain you still feeling like crap on 24 mg's a day of suboxone. I went form $200 a day of IV heroin(for about 4 years) straight to only about 2 mg's of suboxone a day and it was more than enough to m ake me feel great. And the lower the dose I took, the more euphoric I felt from the subs. This makes me wonder that maybe your problem is that your taking too much suboxone....I know that when I take too much, it makes me feel like crap...headaches...tired.....etc...but when I take tiny doses, I feel AWESOME.

sp0r
11-09-2010, 03:49
Despite what has been posten in scientific literature I can tell you first hand ( i have been on subutex since 2004 ) it has a severe withdrawl syndrome, on par with methadone. Maybe even worse. I am kind of a guinea pig for I have been on it since almost the beginning. I was taking it when it was compounded into wax squares. BAD BAD BAD withdrawl trust me.. the PAWS is the worst.



Acute withdrawal symptoms from buprenorphine aren't too terrible (though it is certainly unpleasant) What kills me is the PAWS; which for me means persistent insomnia; weird and seemingly unrelated physical complaints; and difficulty thinking clearly Supposedly; buprenorphine maintenance can facilitate positive changes in brain chemistry Everyone is different of course

Someone had asked earlier about how long it takes for buprenorphine to completely clear your system: I had read an article a few weeks ago about this so I checked it again Apparently; burprenorphine and its metabolites are detectable for a range of 9-14 days; with a median among the test subjects of 11 days

OMG out of all the opiates i have been on (alomost all of them including methadone) buperenorphine is definately the most constipating. I have been constipated for over a month many times. Fucking enemas dont even work. It takes for me that pre copping anxiety to shit. Its terrible I dont know why. Possibally because It binds to almost every opiate receptor (smooth muscle) and when taken daily several times it gets worse and worse.) Be for warned you do not want a doctor pulling shit out of your ass.



Why am i reading about people using like 6mg of bupe sublingually to get off, when im on 24mg a day and i still wake up feeling mildly crap?

Makes no sense, i wasnt even an IV H user for over a month, i guess it dosn't take long... 500mg oxycodone isnt even a substantial amount anymore? That used to be a fucking good stash now its not even a nod(this was just before i got on suboxone).............

I dunno i've just always thought it took months to years to develop a tolerance where one could dose 500mg of oxycodone and not even nod...

Or can natural tolerance play a role, ive always handled by opies better than any of my mates but this is just insanity...


Also reading about the plugging roa, once i get to the point in my program where i get 4 take home doses per week im def gunna be trying this method... fuck lol

jamesBrown
11-09-2010, 05:29
I personally get constipation from suboxone that is at least 20 x's worse than constipation ive gotten from ANY other opiate.....in fact, ive gotten minimal, almost no constipation from other opiates until buperenorphine.

I shit only once a week give or take.

But when I take Activia yogurt on a daily basis I can start shitting daily again after only a week on the Activia. Jamie Lee Curtis your a lifesafever!!!

(This is after taking all kinds of laxatives and whatnot...and even taking multiple doses of different laxatives to try and "open the floodgates" so to speak....but nothing worked)

sp0r
11-09-2010, 06:02
Miralax is good. All it is is propylene glycol however ;)). Milk of mag work better for me .. Except you are up all night with your stomach churning...... Hey for those of u who plug, try snorting two mgs. Its is fucking amazing.. The generic subutex hurt too much.. use name brannd.
have fun.

Covert
25-09-2010, 08:55
The reason I say "~Xmg" (~ means about) is because half-life is not the only factor that contributes to how much drug is in your system. The rate of absorption plays a big role, and can be affected by many things, like method of admin for instance.

The half life is 36 hours. It's solid fact, and no matter what, it will always be 36 hours. Half life is a constant.

The problem here is that you are thinking in terms of radiation half life, and it just does not work like that. You stated in an earlier post that if you take 8 mg of suboxone, then 24 hours later you take 8 more, there will be 12 mg in your system (4 mg from day 1 + 8 mg from day 2). Then, 24 hours after that, you take another 8, and there would be 14 mg in your system (2 mg from day 1 + 4 mg form day 2 + 8mg day 3), but this is not how it works.

The buprenorphine does not simply half itself every 36 hours; ON AVERAGE after 36 hours half of the original dose is present. But, over the NEXT 24 to 36 hours, the rest of this original dose of bupe will be gone. The stuff that is in your system already is not subject to the same "halving every 36 hours" that the original dose was subject to -- ESPECIALLY in a drug like bupe, because its incerdibly high binding affinity degrades,over time, in the body. So these "half-life" questions ignore the fact the the "biological half-life" may be 36 hours, but the biological WHOLE life is somewhere around 70 hours -- depending on original dose, body weight, ROA, length of time you've been using bupe, & a host of other variables. But it is fairly safe and accurate to say that around 3 days (72 hours) after you ingest it, essentially ALL of the bupe is out of your system.

Sorry to "reply" to such an old post but i been readin' this half-life stuff & it's driving me nuts. So I had to put that out there.

Peace ya'll!!

Gunbreach
25-11-2010, 02:04
I have been taking Suboxone for pain since April of 2010. Recently I switched from the pill, 2mg twice daily, to the brand new film. I hated the taste of the suboxone so much I would rather shove it up my ass, literally. Furthermore, my car was robbed last week and a few things were taken from my car, my kindle with a cover (roughly $260) and then half my suboxone prescription. So, in light of this I asked my doctor to switch me to the new film. I still despise the taste and would prefer to administer the medication rectally. However, I have come across a bit of a conundrum. It is much harder to dissolve the film than the pill. Usually I would crush the pill up, pour the powder into a 6ml needless syringe, fill it with warm water and then shake it until it dissolved.

My question is this; what would be the best method to dissolve the film, the taste makes me want to vomit and my psych doesn't want to change me to a different pain medication.

Thank you for your time,

Gunbreach

Please no flaming, duplicate posts or any other nuisances.

~_Hiss_~
29-11-2010, 01:09
snorting it works fine.

i'd imagine a mildly acidic medium like lemon juice might help with rectal, but it might burn too.

f13nd
29-11-2010, 06:27
How exactly do you snort the film? i can only really see that being feasible if its mixed in some sorta solution and sprayed into the nasal cavity

Gunbreach
29-11-2010, 08:00
Snorting the film is not really plausible mainly because it is in film form. Imagine a Listerine Mint Strip only thicker and more mailable. Also, using lemon juice? I imagine would burn like a mother fucker so I am going to pass on that. What you need to do is just get boiling water, fill a needless syringe with the boiling water, cut up the suboxone strip, put the small amount of water into a cup as well as the pieces of the strip, push the water in and out of the syringe (do this for several minutes), once everything is dissolved your good to go. To the people who use suboxone and hate the taste, plugging is a good way to go. It also curbs the nausea and more of the drug is absorbed into the system. Thanks for the responses!




Gunbreach

Captain.Heroin
29-11-2010, 15:32
I merged your post into this thread, as it pertains to this topic well.

JunkBox
23-12-2010, 20:18
Hey guys - i'm new to the forums but i just wanted to add my two cents. I IV roughly anywhere from 2-6 mg's of Bupe a day, depending on how bored I am and how shitty I feel. I've been using Sub's daily for the last ~3 weeks just to maintain, and before that was using Opiates daily, with sub's to stay normal when I didn't have anything. I'm gunna try plugging for the first time, with about a 1mg dose. I'll write back after I do it to let you know my method of plugging, and the effects it had on me. (Written @ 1:42 pm)

(Written @ 2:09) - I prepared my solution the way I would normally do it for IV. I crushed up ~2.3 mg of Bupe and put the powder into a spoon. I then added about 60cc's (a little more than .5mL) of water and dissolved. I filtered it through a cotton into the syringe with no problems at all. If you use a cotton to filter it, the solution will not be too thick to draw up, giving me exactly .5mL. I broke the needle tip off the syringe, and inserted it into my rectum. It was a little uncomfortable, but not too bad. I injected the solution @ 1:42pm and laid on my stomach and watched TV for about 20 minutes. After about 10 minutes I started feeling a little warm and fuzzy, about the same as if I had IV'ed it. After 20 minutes, the effects are still maintaining and I feel decent. No strong euphoria, but a nice glow. Definitely was better than I thought it would be, but I think i'll stick to my IV method. There's something about hitting a vein and watching the blood flow into the syringe that gets me every time. I have about one 8mg Suboxone left, which ill divide into 6 parts and taper myself off over the next 6 days to avoid any withdrawal symptoms. Sorry for rambling, just wanted to provide some insight to plugging from a daily Bupe IV user.

D's
23-12-2010, 20:22
i'd always back load it when i plugg'd, suboxone is watter soluble. i put 4mg in a straw, bend the straw and chew it with my front teeth, when its all powder i'd just back load it in the syringe (without the needle ofcourse..) i lay on my side when i do it, and always used warm water because it feels better. in like 15-20 i feel damn good, i hate the fucking taste of suboxone and this is the only way i go.

i gotta admit, i was doing this shit back to back atleast 3 times a day and didn't shit for 2 weeks. so if u do this dont do it so much.

kanyeknievel
20-01-2011, 18:58
Hey everyone I was just wondering if I was doing this correctly. I have a thin abou 3 inches at the most in length 15ml needless syringe and I take warm water mix the suboxone in and swirl it around. Then I insert the syringe pretty much up to the plungrer and gently squeeze it out. Then slowly remove it and lay on my side for 25mins at the least.

Just wondering I'm I'm doing this wrong or its not deep enough? I do feel it but I don't know if I'm feeling as much as I should. Am I doing this correctly?

Captain.Heroin
20-01-2011, 19:07
It sounds like you are. I am going to merge this into the rectal buprenorphine thread.

axe battler
20-01-2011, 20:46
Hey everyone I was just wondering if I was doing this correctly. I have a thin abou 3 inches at the most in length 15ml needless syringe and I take warm water mix the suboxone in and swirl it around. Then I insert the syringe pretty much up to the plungrer and gently squeeze it out. Then slowly remove it and lay on my side for 25mins at the least.

Just wondering I'm I'm doing this wrong or its not deep enough? I do feel it but I don't know if I'm feeling as much as I should. Am I doing this correctly?

How much bupe are you taking? If it's more than 1.5mg then it could be that you're taking too much to feel euphoria.

Buperenorphine is processed by the body into norbuperenorphine (which is the euphoric one), but this takes a little time. If your receptors in your brain are already full of regular bupe, then there's no room for norbupe.

If you have a tolerance of above 2mg then you'll probably have to taper your dose until you are on less than that.

Is your rectum empty beforehand? It's best to plug just after you've 'made' (shit).

Your plugging technique sounds spot on--our mothers would be proud.

kanyeknievel
21-01-2011, 05:39
How much bupe are you taking? If it's more than 1.5mg then it could be that you're taking too much to feel euphoria.

Buperenorphine is processed by the body into norbuperenorphine (which is the euphoric one), but this takes a little time. If your receptors in your brain are already full of regular bupe, then there's no room for norbupe.

If you have a tolerance of above 2mg then you'll probably have to taper your dose until you are on less than that.

Is your rectum empty beforehand? It's best to plug just after you've 'made' (shit).

Your plugging technique sounds spot on--our mothers would be proud.

I don't take more than 1.5 at a time no. But um, I just realised my syringe is only 1mL :P. Is that too little? I mean its all dissolved in the water and everything so I dont see if it matters? Does it?

stuckinaloop
21-01-2011, 10:23
Why am i reading about people using like 6mg of bupe sublingually to get off, when im on 24mg a day and i still wake up feeling mildly crap?

Makes no sense, i wasnt even an IV H user for over a month, i guess it dosn't take long... 500mg oxycodone isnt even a substantial amount anymore? That used to be a fucking good stash now its not even a nod(this was just before i got on suboxone).............

I dunno i've just always thought it took months to years to develop a tolerance where one could dose 500mg of oxycodone and not even nod...

Or can natural tolerance play a role, ive always handled by opies better than any of my mates but this is just insanity...


Also reading about the plugging roa, once i get to the point in my program where i get 4 take home doses per week im def gunna be trying this method... fuck lol



24mg bupe is a really high dose to be on daily. It seems to me like people near the ceiling dose experience shitty side effects compared to people who maintained on lower dosages.

I read it all the time, someone onlike 24 or 32mg bupe, is in withdrawals before the 24hour mark.

I haven;t tried dosing oxy since I have been shooting dope the past few years, but I will say even switching from 80mg methadone to bupe, I never needed more than 10mg (which was only the first week or so switching from methadone). I have a pretty high heroin tolerance, I shoot around a bundle of NJ dope per shot,,and as long as I force my self to wait it out 24-36 hours (ideally 36) after my last shot of dope, the bupe will hold me (even though it does take like 3-6 days to adjust to the bupe before I am feeling even like 90%.



When I first ever took bupe, I was addicted to oxy, I could take it 12 hours after my last dose of oxy and I would almost even feel high, I would feel like 101%. But that is truely a honeymoon period.

With the dope addiction I have now (and same thing with friends with similar habits), I find that bupe..well for me, it just doesn't seem to work like it used to lol.

But what I have found is that I've switched back and forth so many times, I truely beleive the wait time between your last shot of dope, and first dose of bupe has a enourmous effect on how well the bupe will work.

Lets say I wait 24 hours after my last shot of dope, I take 4mg of bupe. I will not feel great..probably like 60 or 70% good, but increasing my dose does absolutely nothing. I could take another 8mg, 12mg whatever, it does not make me feel any better. I just have to transition. After a few days I can have my dose down to 2mg and feel like 90% good. If I manage to stay on bupe for like 2 weeks, I am feelin pretty solid (but end up using dope lol).

Anyway, my point is, the time to me is more important than the dosage. If I wait 36 hours, or somehow manage to force my self to 48 hours, I get so much more releif than if I took the bupe in like 16 hours after my last dose.

I can take 2mg 36 hours after my last dose and feel better than if I dosed 32mg 16 hours after my last dose

The smaller dosages seem to have less side effects, not to mention your tolerance doesn't skyrocket and withdrawals will be a fucking sinch compared to being on teh ceiling dose for years.

Beerman
26-01-2011, 18:01
^ 100% agree, the effectiveness of the transition from H to bupe is time-dependent and not dose-dependent I think.
I've never tried pluging bupe, I read some posts and I want to try... =D

Gunbreach
27-01-2011, 01:13
1 ml of water for only 1.5 mg is fine, I plug about 4mg but use about 6ml just because that is how large my syringe is. Furthermore, the reason people who take larger doses of Suboxone may feel more intense precipitated withdrawals (that is when you take opiates while on Suboxone) is because of the percentage of the brain each dose covers. Every 8 mgs covers about 33.3% of BBB (Blood Brain Barriers) so people on 24 mgs/day have 99.9% of their brain "protected' (a relative term in this situation). Also, when it comes to precipitated withdrawals the amount of h you take really makes a difference on how much you want to A) wait and B) how much suboxone you take. So if you just dosed I would say stick to 2mg after the 16 hour mark, and every 4 hours increase it by 2-4 mgs. I would just like to add I am not on subs for opiate addiction but for pain I just have some buddies who are on subs for opiate addiction.

Gunbreach
27-01-2011, 01:14
every 2-4 hours until you feel comfortable that is

amanitadine
27-01-2011, 06:05
1 ml of water for only 1.5 mg is fine, I plug about 4mg but use about 6ml just because that is how large my syringe is. Furthermore, the reason people who take larger doses of Suboxone may feel more intense precipitated withdrawals (that is when you take opiates while on Suboxone) is because of the percentage of the brain each dose covers. Every 8 mgs covers about 33.3% of BBB (Blood Brain Barriers) so people on 24 mgs/day have 99.9% of their brain "protected' (a relative term in this situation). Also, when it comes to precipitated withdrawals the amount of h you take really makes a difference on how much you want to A) wait and B) how much suboxone you take. So if you just dosed I would say stick to 2mg after the 16 hour mark, and every 4 hours increase it by 2-4 mgs. I would just like to add I am not on subs for opiate addiction but for pain I just have some buddies who are on subs for opiate addiction.

8mg covers 33.3% of the Blood Brain Barrier, eh? Wow, I never knew.......

( I am assuming this is posted in the rectal buprenorphine thread because it is full of shit?)

Beerman
31-01-2011, 21:43
Every 8 mgs covers about 33.3% of BBB (Blood Brain Barriers) so people on 24 mgs/day have 99.9% of their brain "protected' (a relative term in this situation).
^ LOL, right, 33.3% of BBB? wtf? I don't think that BBB has nothing to do in your explanation. Maybe you mean the opioid receptors, right?
BTW I tried plugging and it feels great. Maybe a little bit more portent than snorted, and it seems kick in faster... I have to try more times, but I don't like that of putting some in my ass and have to lay.. but well, it's better than make holes in my skin and veins (I have to let them some time for repair) and also don't have to deal with the nasty taste of the drip...