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Thread: (Nucynta/100 mg) Experienced: Full Review

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    #26
    Greenlighter mimiikiins's Avatar
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    I have some experience with Nucynta. I was using Roxis for the past year (at the end of my addiction I was using 10-20 Roxi 30mg daily.

    Long story short, I have been clean and sober for 25+ days. I started taking Nucynta a few days ago. Keep in mind while I was taking Roxis I have taken Nucynta a few times and didn't feel ANYTHING. I know it was because my tolerance was so high and I was taking Roxis.
    I have been taking 100-200 mg for the past few days. Compared to a "real" opiate its like tic-tacs. BUT I must say I have felt some relief and that warm fuzzy feeling.
    It takes about 30 min to kick in but once it does I feel at ease.

    I personally feel that it is a great new drug and if people that may want to get off the roxis/oxys and still may need to take pain meds, try this. I would recommend detoxing completely first before trying Nucynta. If you don't, most likely you will not be satisfied with the results.
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    #27
    Since I was recently prescribed this drug and could not find a whole lot of information on it since it is still fairly new, I figured I would post my personal experience with it. Now I use my meds for legit pain relief as I have a bad back (3 jacked up disks/Arthritis) along with being a not so common male chronic migraine sufferer, which doctors believe I inherited from my mother who suffered the same. Back to the point, this week i was prescribed Nucynta ER 50mg. I had to go to 5 different pharmacies before being able to locate this drug... I assume because it was newer. The 4th pharmacy before i got my script filled it with regular Nucynta not the ER, because he had never heard of the ER before me. Keep this in mind if you yourself have been prescribed this med and make sure its right. Even with my insurance it is pretty expensive stuff. I have thus far taken 10 of these (not all at once) and for me personally it has not helped my pain(migraine).

    Also, to add since they weren't working anyway, I decided to attempt something concerning crushing. I went as far as pulling out my mortar and pestle and could not for the life of me crush the Nucynta ER. Seems the ER is uncrushable, save for maybe a tank running over it.
    Last edited by PHDnPain; 06-01-2012 at 17:43.
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    #28
    Its cause it has a bit of anti depressant in it as well. It is also and SSRI while being and opiate.
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    20 percent ssri and 80 percent u-upiate 
    #29
    Its cause it has a bit of antidepressant in it. Its a 20% SSRI and 80% u-opiate
    Quote Originally Posted by q_werty View Post
    Thanks for the review.

    I am set to pick mine up today to try it out.

    Currently on percocet 10mg 4 x a day. which is better than nothing but I havent had any significant pain relief in almost 5 years.

    So while I am not entheusiastic , given the nature of my condition anything can happen, so hopefully nucynta will help the pain.
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    Nuycynta acts more like Lexapro crossed with vicodin and adderall 
    #30
    For those of you looking into Nucynta or have been prescribed it, it is a very different and weird opiate/pain killer. I was prescribed 100MG 3 times a day for a lower back/spinal vert. and colitis pain management. It did somewhat help with the pain but very very minimal. It should not be compared to morphine nor percecet 10 MG. You can feel the opiate feeling but my experience with this is that it was more of a mood elevating/boost of energy type drug. I did not find it to be sedative at all. It felt like a mix of adderall-lexapro-and vicodin-5MG. it made me very jittery and twitchy. Nucynta in my opinion should be used for fibromyalgia, depression, and very minimal types of pain like a sprained ankle or some sort of fall. After paying a ton of money i ended up being switched to Dilaudid 2MG which in my opinion is the best pain reliever that you can take orally. Oxymorphone is probably the best option to go with for those with moderate to severe pain and chronic pain that needs to be managed.
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    #31
    "Swim" pretty much nailed it. about 100mg is equivalent to a combination of about 10mg ambien and 10mg hydrocodone, minus the itch. haven't snorted it though.
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    #32
    Reviving an old thread. My first post here. Just got done going thru wd's from morphine becouse the pain management dr. prescribed nucynta er to replace the morphine sulfate er. I was taking only 30mg morphine sulfate er every 12 hours for about 6-7 weeks. I asked for something comparable that would maybe not give the constipation and headaches that morphine does. I also asked if I would go thru the wd's changing over and He said "no". So He prescribes nucynta er 100mg every 12 hours to replace the morphine sulfate er 30mg every 12 hours. 24 hours into the switch here come the hot flashes, headache, nausia.....So I quit everything. I am now 48 hours clean off all opiods. Feel pretty good mentally today. Yesterday (day #3) was hell! Of course the back pain I was taking morpine for to begin with has returned in full force, but what can you do? Back to the ibuprofins I guess. Currently undergoing spinal decompression. Thinking of getting an epidural asap so I can function. My main reason for posting here is just to add to this report and to inform anyone who is considering switching to nucynta from morphine to expect the wd's.
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    #33
    Ok. So I have a very high tolerance for oxy codone and hydromorphone also morphine and have been mainin them for years so when nucynta came out I tried a 50. It did nothing. More recently I heard they could be mainlined. So I cooked 200 mg's filter with q-tip head and found a vein and plugged it. Burns like hell no real opiate full body buzz/ rush that u would get with dilaudid or morphine.more of a gentle onset. Then a buzz comparable to taking alot of tramadol. Which makes sense since tramadol and nucynta are in the same family. Point is that if you are a heavy user of real opiates this stuff is for the birds.
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    #34
    I wanted to let everyone know a little about "Nucynta", or "tapentadol" (chemical name). Once a patent runs out, other pharm companies use the chemical name for sale of product. My husband is a Pain Management Doctor (named one of the top 10 in country), he has been practicing in Dakota Dunes, SD for 18 years. I am really frustrated with hearing "Tapentadol is similar to Tramadol", on the contrary, it is not really similar in structure to anything we have seen in 25 years. My husband says that it is complete garbage to consider the possibility of this new drug being anything like Tramadol. It is more like Demerol, hitting the mu opioid receptor which produces effects ranging from slight euphoria, hallucinations, and sedation. Please do not compare this drug to something that is not an opiate. Tramadol is considered to be more of an SNRI analgesic chemically unrelated to true opiates. It is a "big gun" as my husband calls it. It is also given to people the docs believe are drug seekers because it does not produce the true euphoria, possibly because of the SNRI component. I am a counselor, and have worked with adolescents my whole career, I have seen drug seekers. Nucynta is a Schedule II opioid antagonist, somewhat similar to Methadone in side effects. So, if a patient comes right back in to see the doc because this is not working, most docs will see it as someone who just wants to get high. I am also a pain patient, I am very patient because it is basically trial and error because pain is subjective. You have to be very honest with your Dr., they will take good care of you, and give you what you need if you ask for it, but do not abuse it. My email is [email protected] if anyone has any questions about different pain treatments, I can consult with my husband and give you accurate info. I am on these boards a lot, and I see a lot of self-righteous indignation from people who think they know more than there Dr.'s; however, they cannot even spell medical terms correctly. The most dangerous aspect of people that think they know it all is that others are naive enough to believe it. No drug is going to completely get rid of your pain. If you go to a Pain Specialist, do injections first, do not question their techniques. These days, the Government is all over the PM docs about handing out these meds. If you want meds initially, and refuse the injections, they will see you as a drug seeker, you might get "fired" as they call it, then put into a system. They arrest people who come in and say they "lost their pills", btw. These doctor's are doing you a favor, every time they write a script, they have to cover their asses.
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    #35
    Bluelighter Thou's Avatar
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    Tapentadol for anyone who wasn't firmiliar with this medicine.

    I'm going for a swim.

    Be back in a minute

    _

    Okay.

    Quote Originally Posted by Captain.Heroin View Post
    Thank you.

    We don't do SWIM here; there's 2 threads - one stickied, one not - all about how we don't use SWIM. It's also in the OD posting standards.

    Plus, this is a Trip Report, am I right?

    OD -> TR
    I just got out of the grammatical pool and the water sucks today.

    Thanks for the report. BLUA agreement is right in my signature please read before posting everybody, cheers.

    Thou

    I have nothing to add about this opiod but it sounds like a decent medicine if used properly. I'm not really an opiate guy, not that I'm against them. Not my cup of tea.

    Helped my friend hit a vein the other day and declined a shot for myself. Never IV'd a drug myself before, but was happy I had come with nitrile gloves, alcohol pads, lighter for sterilization, sterile saline, etc. She was shooting suboxone that was a digression, was an interesting learning experience for me especially considering her veins were shot and the spike she was using was one of those shitty 33m tuberculin syringes. Horrible. But she registered good with no ill effects. I took a little bump, woke up itching my ass off remembering why I don't usually take opiates and took two klonopin to control the itching (common symptom of gabaergic WD for me is histamine release).

    Sorry for the tangent I'm fascinated in the IV drug culture though so wanted to add my little first experience with it.

    Nuycynta acts more like Lexapro crossed with vicodin and adderall
    This sounds like a terrible combination to me, but everyones mileage will certainly vary.
    Last edited by Thou; 15-12-2012 at 19:07.
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    #36
    Greenlighter yonkers's Avatar
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    I would prefer nucynta over H any day. When i first got into opiates i would get the nucies 100mg. Usualy take 1-2 at first but then started taking 3-4 (snorting) burned like hell, but i ended up enjoying the burn. Shooting these pups up were great, pretty sure it was my first drug IVED.

    Maybe i only like it so much cause i cant get it anymore. I would easily hallucinate on these in a dark room off of 2-4, very pleasant. Hallucinations similar to a large dose of benadrly but no body discomfort, just really sedating and chill drug. I got them really cheap so it was awesome while it lasted. Deffently not as strong as dope, but I would pay good money for another sesh with my nucie baby
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    #37
    Greenlighter yonkers's Avatar
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    Hey to anyone that pm'd me on how to bang these, i cant reply yet since im a greenlighter. But make sure you get the orange coating off of the pill using water so you're left with a white pill. Then simply crush and add water. Its not a huge rush but its deffently there. I replied to your message then realised it didnt send so sorry i couldnt give you an answer via msg.

    If you're planning on banging more then two pills then you may need a 3cc syringe. For every 100mg pill add around 70 units of water. You wont get all of it back, sorry this was awhile back so sorry if im off a bit. Idk how safe this is but ive done it prolly around a hundred times a few years ago and im fine. Dont add heat to the solution. Simply stir and filter.

    MAKE SURE THE ORANGE COATING IS OFF. Hope this helped. Injecting pills isnt safe but if you're going to do it then make sure you're not adding heat and filter a few times
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    From SUBOXONE to NuCYNTA 
    #38
    I started taking Nucynta IR 75mg nine days ago (1 pill every 4 hrs). I was currently taking at least 8 mgs of Suboxone daily, sometimes up to 24 mgs (addicts generally take more of everything, especially medication). The reason I had to quit suboxone is because I am having my second spinal fusion (L4-S1). The neurosurgeon wants me to be completely of suboxone at least for 2 months. He just wants to know for sure that I will be responsive to opiates in post-op.
    I have been on ridiculous amounts of almost every opiate a doctor can prescribe. When I explain the effects Nucynta is having on me, I don't want anyone questioning my past experiences. With that out of the way, lets get into describing the transistion. I was surprised to find that I had zero WD's from suboxone. Obviously it was from keeping a steady flow of Nucynta in me. For the first 6 days I didn't really feel anything. I wasn't high and not sick. Day 7 I woke up and took 2 and half pills. I smoked a bowl, drank some coffee... BOOM!!! I def got that great warm feeling. After about two hrs I started getting very itchy and having some considerable nods too. I have been reading a lot about people complaining that nucynta is shit and what not. This is my final thought on Nycunta: they absolutely will keep the wd's away. And if you have not much tolerance then you will for sure catch a nice buzz if you eat 1 or 2 of these. PS.... these are nothing at all like tramadol. Nucynta is a CII and I understand why, they will get you fucked up and I def see potential for abuse.
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    #39
    Greenlighter yonkers's Avatar
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    If I could get a nucy script id be off subs in a heart beat. I really wana get off it too but nucys all day wouldn't help
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    #40
    Ive been prescribed tapentadol er for a while now, it doesnt seem to have any effect on me, i have quite a high tollerance. as i cant find a way to prep these to shoot i decieded to give plugging a go. i didnt expect but bot was i wrong, 100mg er has given me a very europhic nod (not unlike 50mcg 25mcg fentynal extracted and iv'd completely to my surprise!!! Just thought id throw in my 2 cents (haha even know i should say 2 pennies as im from the uk). I would highly recomend it as the oral biovaibility seems rather low. i used to be a big tramadol lover, but for me the way forward is to plug tapents.
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    #41
    I have recently been prescribed Nucynta ER100 mg, after being on everything from oxymorphone, oxycontin, Mscontin, ect. Due t stomach ulcers, I find that snorting pills not only prevent more stomach pin, but allow the pain medication to work much faster. Does anyone know of a way to make these gummy-like pills change into something crushable? Please help! I have contacted my doctor to try to change the meds back, but it may take week for a response! Am grateful for any and all suggestions to get me through!!

    With Thanks,

    AngelWing
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    #42
    Shadowmeister
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    Try plugging (rectal administration). It is even stronger than plugging and also takes effect very quickly. It's comparable to IM injection in dosage and effectiveness.
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    #43
    Quote Originally Posted by ohline View Post
    have yet to see this drug around, but from what i've heard from a majority of people who have tried it, it's shit.

    also, we do not use "SWIM" here. check out the stickies at the top of the OD section.
    I'm New to forums, wtf is swim?
    I've been experimenting with nucynta and have found it to be very enjoyable. I'm am not, however, a regular opiate user. I take lyrica so that is likely adding to the effect of this drug. I took hydrocodone on lyrica and boy did it intensify things. I only took two 10's and drank a few beers and had me a good old time! Same with nucynta. I have been cutting them in half so they hit faster. I have tried plugging. First time it was Fabulous! Second time, nothing. I might try cutting one in half and plugging. I'll report back if I do.
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    #44
    Shadowmeister
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    SWIM stands for "someone who isn't me". Some forums require you to say SWIM instead of "I" or "me" under the belief it would somehow protect you... which is false. Since it's annoying to read, we don't allow it here.
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    #45
    Greenlighter Noctis88's Avatar
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    God I hate the stuff, not to mention the negative psychic effects it has.
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    #46
    A year ago I was involved in very bad accident. A minivan hit my with 60 mph on the driver's door breaking my pelvis. I am lucky to be alive. I had 3 surgeries and they put 5 chains and 16 pines in me. For the last 1 year I took more pills than my grandma ever did in her life, so I have experience with different painkillers. In the hospital I was on dilaudid and percocet 10/325. After I was discharged I was 2 months on Percocet 10/325, Oxycodone 5mg (pure), Gabapentin 600mg and Tramadol 50mg. Then they switch the Percocet with Norco 10/325, after another month with Vicodin 5/350 + Lyrica for the nerve pain. During the summer I was on Tramadol only, but now with the cold season the pain got worse again, and the doctor prescribed me Nucynta 100mg.

    This medicine is definitely not shit. Most of the people hate it because it doesn't give you the high. Well I am sorry but these pills are made to KILL your pain, not only to give you high, this is just a side effect. In my experience I find Nucynta more powerful than the Norco for the pain and the effect lasts much more. It doesn't give you euphoria but definitely gives you warn and calm feeling not messing with your head (if you take it as prescribed ofcourse). Because of the many junkies lately simulating pain just to get their hands to the narcotics, now these pills are much harder to prescribe to people like me who really needs these kind of medicine. I had to go to 5 different doctors to finally someone believes me that my pain is real and give me pills that help for my pain.

    If you really have sharp pain that OTC or Tramadoll pills can't help with I really recommend Nucyntia. If not and you are trying to get high find another medicine, but please don't say it's shit, because it ISN'T !
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    #47
    I got 8 100MG IR of these for free, pill id was (O-M 100) to me these are very strong, I had little to no tolerance and took just 1 and was nodding like crazy, I couldnt keep my eyes open. I have 3 and 1/2 more. These are great, but wish they lasted longer. I did every route of administration, besides plugging. I smoked, snorted, and ate them. Smoking is stupid and bad I have a weird habit with smoking opiates but fuck smoking pills. Snorting worked quite good but burns worse than anything, would no advise unless you dont give a fuck about pain. None of these ways got me nodding besides swallowing them, and damn. Once you swallow them, it hits you like a freight train, 30 mins later im nodding like hell. For sure a potent opiate.
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    #48
    Quote Originally Posted by thagumbi View Post
    For those of you looking into Nucynta or have been prescribed it, it is a very different and weird opiate/pain killer. I was prescribed 100MG 3 times a day for a lower back/spinal vert. and colitis pain management. It did somewhat help with the pain but very very minimal. It should not be compared to morphine nor percecet 10 MG. You can feel the opiate feeling but my experience with this is that it was more of a mood elevating/boost of energy type drug. I did not find it to be sedative at all. It felt like a mix of adderall-lexapro-and vicodin-5MG. it made me very jittery and twitchy. Nucynta in my opinion should be used for fibromyalgia, depression, and very minimal types of pain like a sprained ankle or some sort of fall. After paying a ton of money i ended up being switched to Dilaudid 2MG which in my opinion is the best pain reliever that you can take orally. Oxymorphone is probably the best option to go with for those with moderate to severe pain and chronic pain that needs to be managed.
    I'm sorry but do you suffer from Fibromyalgia? I do and unless you know what it's like you shouldn't assume that one medicine is best for a condition. I was on everything from Fentanyl to Opana and they didn't even help me. Fibromyalgia does not cause minimal pain. Shame on you for assuming that.
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    #49
    Shadowmeister
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    I think he was saying, it should be used for fibromyalgia and things that cause minimal pain, not that fibromyalgia causes minimal pain.
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    #50
    I have been on Nucynta IR for two months for moderate/severe lower back pain. It works. I have a compression fracture in my lower back. Percocet didn't help in any way except make me high for about 20 minutes and then sick. Same for Hydrocodone. Nucynta actually kills the pain and I can still think clearly. I do not take extended release, only IR. Huge difference. Night and day. Anyway, on a relatively empty stomach 75mg to 150mg hits me in about 20 minutes, keeps getting stronger for about an hour and then levels off. Long lasting pain relief and makes me feel very social/chatty. Ive been prescribed Percs, Vics, Oxo. They all just get you high and ware off quickly. Nucynta kills pain, and has a nice euphoric element to it.
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