Bluelight

Synthetic Cannabinoids Study

Thread: Case Study: Tren Causes Heart Attack in 23yr Old

Results 1 to 15 of 15
  1. Collapse Details
    Case Study: Tren Causes Heart Attack in 23yr Old 
    #1
    Moderator
    Performance Enhancing Drugs
    CFC's Avatar
    Join Date
    Mar 2013
    Location
    The Yoo Kay
    Posts
    1,947
    Bluelight
    Just putting this one out here for a read. A 23 year old male Iranian bodybuilder suffered a heart attack (myocardial infarction/MI) in 2014 as a result of stenosis (narrowing) of his coronary arteries caused by trenbolone. Have a look at the free study >>here<< for pictures.

    For anyone reading this forum, the fact that a bodybuilder had an heart attack from AAS use is hardly news. However I thought it worth posting since it's about tren, and there's a growing army of hopeful 'Instagram models/supplement ambassadors' presently drowning in the stuff in order to achieve that thick, cut, hard look that tren's famous for.

    As the Iranian doctors discovered: "it was elucidated that he had been using Trenbolone Acetate in his daily diet since last year," and this paper was published in the winter. So though we can't determine exactly how long he was using, or whether it was part of a larger stack of AAS (probably), he was clearly on for too long!

    The bodybuilder was fit and otherwise healthy, so his coronary stenosis was almost certainly related to the use of AAS. If you want to understand the pathogenesis of AAS-induced stenosis and MI in otherwise healthy bodybuilders, have a quick read of this previously posted case study (which also discusses thrombi formation).

    As always the take home message is keep doses sensible and take decent breaks from cycles. Time on = time off is still a useful minimum rule-of-thumb.


    Anyway, here's the abstract:


    **********

    Emerg (Tehran). 2014 Winter;2(1):43-5.
    A Young Man with Myocardial Infarction due to Trenbolone Acetate; a Case Report.
    Shahsavari Nia K, Rahmani F, Ebrahimi Bakhtavar H, Hashemi Aghdam Y, Balafar M.

    Abstract


    Over the last four decades, a significant decrease has been observed in age-related mortality caused by cardiovascular disease. People in developing countries suffer from CAD at a relatively younger age and about half of MI occurs under the age of fifty years. Abuse of anabolic steroids is one of the less common causes of atherosclerosis. In this report, a 23-year-old male body builder referred to emergency department (ED) with myocardial infarction (MI) following chronic Trenbolone acetate consumption. It seems that a comprehensive history of steroid consumption in young patients referred to ED with the chief complaint of chest pain or its equivalents is necessary in adjunct to other cardiac risk factors.


    ***********


    Full free paper:
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614617/
    Last edited by CFC; 10-01-2017 at 21:59.
    Reply With Quote
     

  2. Collapse Details
     
    #2
    Moderator
    Performance Enhancing Drugs
    Genetic Freak's Avatar
    Join Date
    Mar 2012
    Location
    New Zealand
    Posts
    1,887
    Almost unheard of MI at 23.... Makes me wonder if the pt' was genetically predisposed to thrombus formation and subsequent rupture, either from family history or just bad diet from early age, and Tren' plus whatever else he'd taken in combo or prior to tren' was too much for his coronary arteries... (don't AAS potentiate platelet aggregation)..

    Quite extensive L sided ST elevation on 12-lead V1-V6, wonderful what they can do with a stent, in-out and on their way home in 2 hours...
    Reply With Quote
     

  3. Collapse Details
     
    #3
    Moderator
    Performance Enhancing Drugs
    CFC's Avatar
    Join Date
    Mar 2013
    Location
    The Yoo Kay
    Posts
    1,947
    In this case it's probably moreso the arteriosclerosis --> stenosis that led to his MI rather than a clot per se. While there's likely (certain?) to be a genetic component in his vulnerability to stenosis, and also perhaps acute issues like dehydration (maybe diuretics), I think we have to admit that the clusterfuck of side-effects related to a strong AAS like tren ('sticky' platelets, fibrosis and arterial stiffening, poor lipids>fatty deposits and plaque formation, CNS stimulation, elevated RBCs etc etc) are still at the heart of the issue. More background info would have been helpful.
    Reply With Quote
     

  4. Collapse Details
     
    #4
    Moderator
    Performance Enhancing Drugs
    Genetic Freak's Avatar
    Join Date
    Mar 2012
    Location
    New Zealand
    Posts
    1,887
    Quote Originally Posted by CFC View Post
    In this case it's probably moreso the arteriosclerosis --> stenosis that led to his MI rather than a clot per se. While there's likely (certain?) to be a genetic component in his vulnerability to stenosis, and also perhaps acute issues like dehydration (maybe diuretics), I think we have to admit that the clusterfuck of side-effects related to a strong AAS like tren ('sticky' platelets, fibrosis and arterial stiffening, poor lipids>fatty deposits and plaque formation, CNS stimulation, elevated RBCs etc etc) are still at the heart of the issue. More background info would have been helpful.
    Stiffening, and narrowing at such a young age, we'd normally be treating pt's in their 50-60's for that presentation.. I'm hoping he is a one off..
    Reply With Quote
     

  5. Collapse Details
     
    #5
    Moderator
    Performance Enhancing Drugs
    CFC's Avatar
    Join Date
    Mar 2013
    Location
    The Yoo Kay
    Posts
    1,947
    It is scary mate. I would like to encourage guys who are serious into bodybuilding and use a lot of AAS to get their coronary arteries and aorta looked at from time to time, privately if need be. It's a small price to pay for peace of mind.
    Reply With Quote
     

  6. Collapse Details
     
    #6
    Moderator
    Performance Enhancing Drugs
    Genetic Freak's Avatar
    Join Date
    Mar 2012
    Location
    New Zealand
    Posts
    1,887
    Quote Originally Posted by Genetic Freak View Post
    Stiffening, and narrowing at such a young age, we'd normally be treating pt's in their 50-60's for that presentation.. I'm hoping he is a one off..
    Shit.. I've just realised, that's where I'm at..
    Reply With Quote
     

  7. Collapse Details
     
    #7
    Moderator
    Performance Enhancing Drugs
    CFC's Avatar
    Join Date
    Mar 2013
    Location
    The Yoo Kay
    Posts
    1,947
    You had your arteries looked at a couple years ago though didn't you? Or am I misremembering.
    Reply With Quote
     

  8. Collapse Details
     
    #8
    Moderator
    Performance Enhancing Drugs
    Genetic Freak's Avatar
    Join Date
    Mar 2012
    Location
    New Zealand
    Posts
    1,887
    Quote Originally Posted by CFC View Post
    You had your arteries looked at a couple years ago though didn't you? Or am I misremembering.
    You are correct.. although only carotid via ultrasound..
    Reply With Quote
     

  9. Collapse Details
     
    #9
    Bluelighter Intense's Avatar
    Join Date
    Feb 2014
    Location
    A booty
    Posts
    394
    I'm assuming it was due to his dosage/duration/diet with the biggest factor here being a genetic predisposition to cardiovascular issues.


    You also hear about these middle eastern guys taking it to the limit in regards to dose/duration of the drugs. Add in the quality of gear these guys are getting(which is supposedly some of the best, I may be wrong) and the lack of blood work/monitoring of their health and you have a recipe for something like this to happen it seems.


    To them reading online seeing guys taking 700 - over 1000mg of tren a week, which is usually under dosed UGL gear here in the states. But there it could be overdosed etc..

    A lot of factors at play.



    This is good information that needs to get out there, especially with like you said the insane number of Instagram celebs preaching the use of tren in every other post. Which is being viewed by very young audiences.



    I myself am even guilty of running tren for far too long and far too high of a dose, but will never do that again. No telling the long term effects even that run is going to have on me down the road, but I chose to do it.
    Reply With Quote
     

  10. Collapse Details
     
    #10
    Moderator
    Performance Enhancing Drugs
    CFC's Avatar
    Join Date
    Mar 2013
    Location
    The Yoo Kay
    Posts
    1,947
    I'm assuming it was due to his dosage/duration/diet with the biggest factor here being a genetic predisposition to cardiovascular issues.
    While genetics probably played a role, we don't know that for certain, and so can't allow ourselves to get complacent. Too many guys kid themselves that it won't be them, but the alarming number of people developing dangerous side effects from AAS suggests otherwise.

    You also hear about these middle eastern guys taking it to the limit in regards to dose/duration of the drugs. Add in the quality of gear these guys are getting(which is supposedly some of the best, I may be wrong) and the lack of blood work/monitoring of their health and you have a recipe for something like this to happen it seems.
    Yeah, I get that impression too, with AAS and ancillaries more readily available through legitimate pharmacies out there. Though who really knows whether they take more or less precautions than the rest of us.

    I myself am even guilty of running tren for far too long and far too high of a dose, but will never do that again. No telling the long term effects even that run is going to have on me down the road, but I chose to do it.
    Fortunately many of the invisible side effects can partially or fully reverse with time off AAS and lower doses, assuming high exercise volume and healthy diet is maintained.
    Reply With Quote
     

  11. Collapse Details
     
    #11
    Moderator
    Performance Enhancing Drugs
    Genetic Freak's Avatar
    Join Date
    Mar 2012
    Location
    New Zealand
    Posts
    1,887
    Quote Originally Posted by CFC View Post
    .
    Fortunately many of the invisible side effects can partially or fully reverse with time off AAS and lower doses, assuming high exercise volume and healthy diet is maintained.
    What would you advise as a minimum for high exercise volume, it's something I've neglected over recent years... I try for 10-15km twice a week on my mountain bike if I can, with a couple of sprints thrown in along the way..
    Reply With Quote
     

  12. Collapse Details
     
    #12
    Moderator
    Performance Enhancing Drugs
    CFC's Avatar
    Join Date
    Mar 2013
    Location
    The Yoo Kay
    Posts
    1,947
    The biking + sprints is good GF. You could add a session of running if you felt up to it? Just 30-40 mins medium intensity, with 2-4 x 15 second all-out sprints thrown in for good measure.

    The benefit of some running over biking is that it should improve your joints (upregulate chondrocyte output). Otherwise, another session of the biking + sprints would suffice just for the cardio.

    How is your blood pressure doing nowadays mate?
    Reply With Quote
     

  13. Collapse Details
     
    #13
    Moderator
    Performance Enhancing Drugs
    Genetic Freak's Avatar
    Join Date
    Mar 2012
    Location
    New Zealand
    Posts
    1,887
    Quote Originally Posted by CFC View Post
    The biking + sprints is good GF. You could add a session of running if you felt up to it? Just 30-40 mins medium intensity, with 2-4 x 15 second all-out sprints thrown in for good measure.

    The benefit of some running over biking is that it should improve your joints (upregulate chondrocyte output). Otherwise, another session of the biking + sprints would suffice just for the cardio.

    How is your blood pressure doing nowadays mate?
    110/70 after leg day sunday... 150/90 last week after 3 coffees n quite stressed, so intermittent, but mostly on the low side..
    Reply With Quote
     

  14. Collapse Details
     
    #14
    Moderator
    Performance Enhancing Drugs
    CFC's Avatar
    Join Date
    Mar 2013
    Location
    The Yoo Kay
    Posts
    1,947
    Much improved then! Try a big mug of super-strong cocoa when downing the coffees to relax the arteries
    Reply With Quote
     

  15. Collapse Details
     
    #15
    Tren is a fucking horrible drug, seriously.... No more than 100mg E3D of this shit is ever needed for anyone who remotely gives a damn about their body. Anyone using more than that is either insane or getting fake shit

    I've just dropped using it entirely, there isn't a reason to really use it honestly... No way in hell would I ever combine any stims with it.

    Thing is, anavar + test gives me the same androgen receptor bla blah benefits and literally 0 side effects. Tren has such bad sides compared to other hormones its strange, I stopped using tren entirely, added ghrps mainly pre-training and made much more gains.
    Last edited by SamStick; 23-01-2017 at 22:30.
    Reply With Quote
     

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •