I have a chronic stomach condition that is often not that well controlled. It makes me extremely sensitive to getting nauseated and my stomach is very sensitive in general. Psilocybin mushrooms have become completely unbearable for me to take. I'm just horribly nauseated the whole time. I haven't taken them in several years because of how miserable I become. I have a prescription for Ondansetron I use to help control my condition and it occurred to me the other day that is might be the perfect solution to allow me to partake once in a while. Seeing as it is a 5-HT3 antagonist, I feel it would be very effective in preventing mushroom-associated nausea.
Does anyone have any input on this? Is it 100% safe?