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FDA approves new hand-held auto-injector to reverse opioid overdose

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April 3, 2014
By Sandy Walsh / FDA NEWS RELEASE

The U.S. Food and Drug Administration today approved a prescription treatment that can be used by family members or caregivers to treat a person known or suspected to have had an opioid overdose. Evzio (naloxone hydrochloride injection) rapidly delivers a single dose of the drug naloxone via a hand-held auto-injector that can be carried in a pocket or stored in a medicine cabinet.
It is intended for the emergency treatment of known or suspected opioid overdose, characterized by decreased breathing or heart rates, or loss of consciousness.

Drug overdose deaths, driven largely by prescription drug overdose deaths, are now the leading cause of injury death in the United States – surpassing motor vehicle crashes. In 2013, the Centers for Disease Control and Prevention reported the number of drug overdose deaths had steadily increased for more than a decade.

Naloxone is a medication that rapidly reverses the effects of opioid overdose and is the standard treatment for overdose. However, existing naloxone drugs require administration via syringe and are most commonly used by trained medical personnel in emergency departments and ambulances.

“Overdose and death resulting from misuse and abuse of both prescription and illicit opioids has become a major public health concern in the United States,” said Bob Rappaport, M.D., director of the Division of Anesthesia, Analgesia, and Addiction Products in the FDA’s Center for Drug Evaluation and Research. “Evzio is the first combination drug-device product designed to deliver a dose of naloxone for administration outside of a health care setting. Making this product available could save lives by facilitating earlier use of the drug in emergency situations.”

Ex-officer: War on drugs 'far worse' than a failure

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I dont know about you guys but that vehicle makes me smile from ear to ear=D

bluelight featured in vice.com article on web resources for drug users

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Vice magazine recently interviewed bluelight owner, Sebastians_Ghost for as piece on how internet communities are increasingly serving as sources of information for a wide spectrum of drug users: In a World of Opiate Addicts, the Internet Plays Doctor and Therapist

Bluelight's future: Exciting developments and a call to action

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Dear Bluelight Family:

We write to you with something we find uncomfortable to address, but requires your attention nevertheless - yours, mine, everyone's.

In short, Bluelight needs your help. Today.

As Bluelight has grown, so has the need for better servers and bandwidth, improved software, and a proper domain name. In fact, every penny that comes into Bluelight goes right back out in the form of site maintenance (server fees, software and server upgrades).

We've assessed Bluelight's needs and are ready to upgrade our servers with advanced hardware and software capable of supporting us well into the future. However, these upgrades are not cheap and will increase our monthly operating costs. As it stands, Bluelight costs approximately $8000 a year to run before we factor in the upgrades. As mentioned, we run as lean as possible -- no salaries, no personal equipment, no administrative costs whatsoever. We do this so as not to burden the community and to keep Bluelight...

UK police chief: To reduce crime, we must end the war on drugs

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Just saw this on the BBC website. I'm shocked on 2 counts. 1, that an ACTIVELY serving chief police officer has come out and said this, and 2, that the guy happens to run the force that's only the next county over from me.

B.C. doctors given Health Canada approval to prescribe heroin

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That's fantastic.

Slowly, the fascist walls of this war on drugs have begun to crumble.

Harper and his hidden agenda Conservatives know their ulterior motive anti-drug policies have begun to lose their sway. In the face of new or recent, science-driven, factual ideology, adults of all ages who once stubbornly walked and talked the path of the Conservative, have begun to embrace the truth. And I rejoice for being alive to witness the recent events of late which have contributed to slowly but surely undermining this 40+ year-old war on drug users which has caused untold amounts of irreparable damage since its inception, ironically by a crooked president.

I optimistically await the day, when no one has their freedom snatched away because they felt the need to self-medicate or experiment with a psychotropic substance. A day when we shall look upon the so-called "war on drugs" in bemusement and sadness at the hands of capitalist hypocrites who where in a position to stop or avoid...

Let's Get Frank about Drug Use and Prevent Future Music Festival Tragedies

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Pretty good article I guess.

CDC Issues Alert On Deadly New Designer Drug, Acetyl Fentanyl

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Notes from the Field: Acetyl Fentanyl Overdose Fatalities — Rhode Island, March–May 2013

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6234a5.htm

August 30, 2013 / 62(34);703-704

In May 2013, the Rhode Island State Health Laboratories noticed an unusual pattern of toxicology results among 10 overdose deaths of suspected illicit drug users that had occurred during March 7–April 11, 2013. An enzyme-linked immunosorbent assay (ELISA) for fentanyl in blood was positive for fentanyl in all 10 cases, but confirmatory gas chromatography/mass spectrometry (GC/MS) did not detect fentanyl. The mass spectrum was instead consistent with acetyl fentanyl, a fentanyl analog. Acetyl fentanyl, a synthetic opioid, has not been documented in illicit drug use or overdose deaths, and is not available as a prescription drug anywhere. Animal studies suggest that acetyl fentanyl is up to five times more potent than heroin as an analgesic (1).

During May 14–21, 2013, CDC and Rhode...

Obama administration to allow recreational marijuana laws to stand

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This will be very interesting. Let's see if he calls off the alphabet boys now.

LSD and Other Psychedelics Not Linked With Mental Health Problems, Analysis Suggests

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Science Daily

Aug. 19, 2013 — The use of LSD, magic mushrooms, or peyote does not increase a person's risk of developing mental health problems, according to an analysis of information from more than 130,000 randomly chosen people, including 22,000 people who had used psychedelics at least once.

Researcher Teri Krebs and clinical psychologist Pål-Ørjan Johansen, from the Norwegian University of Science and Technology's (NTNU) Department of Neuroscience, used data from a US national health survey to see what association there was, if any, between psychedelic drug use and mental health problems.

The authors found no link between the use of psychedelic drugs and a range of mental health problems. Instead they found some significant associations between the use of psychedelic drugs and fewer mental health problems.
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