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Stimulants Amphetamines and depression

Vrachox

Bluelighter
Joined
Sep 20, 2022
Messages
64
I am 25 years old male,,i was depressed,anxious,ocd,bod,adhd since i can remember.
When i was 12 years old i was diagnosed depression and medicated,,im these 13 years i tried all sati,snri,trycilic,tetracyclyc,atypical antidepressant,,i was also prescribed few antypsihotics,,mood stabilizers and a lot of benzos.
Notthing helped,,i got tms and finally ect and it helped a little for a while.
I was suicidal,lazy,unmotivated...and then one day my ex gave me dexedrine,,that changed everything i was completley depression free,,iz calmed my mind etc.
I tried everystimulant that exist and they all work very well.
Unfortunetly in my conuntry there is no medication for adhd so i need to self medicated with amphetamine paste.
Any explanation why stims make me symptom free,,,and i appreciate all comments on harm reduction related to amphetamine paste.
Tnx much love
 
Amphetamines, including Ecstasy up until 2003, are *superb* anti depressants. Right now, the only one I can get is Wellbutrin (bupropion), which is a cathinone technically, but cathinones themselves are nevertheless a subset of amphetamines. Also, Benzedrex (propylhexedrine), but they just halved its dosage per inhaler to 250 mg.

I've never had amphetamine paste, but I would give it a try.

My therapist seemed to take it personally when I turned down Strattera, a Prozac analogue and one which I've already tried, for ADHD today.

Wellbutrin only works well when snorted.
 
I tried wellbutrin it did nothing,,straterra also nothing i am currently on few lines of paste a day and it Works Like magic.
 
I've never had amphetamine paste, but I would give it a try.
It's garbage. Speed paste is only worth it when you wash it at least 3x with acetone and even then it makes you feel wired due to the levo component. It's perhaps one of the most cut drugs out there, often not exceeding 10% in purity, the rest being toxic byproducts, caffeine and other cuts which make the high very antsy, jittery and give you a horrible crash. If possible, take dexamphetamine. It serves its purpose as an anti-depressant way better than speed ever will.
 
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It's garbage. Speed paste is only worth it when you wash it at least 3x with acetone and even than it makes you feel wired due to the levo component. It's perhaps one of the most cut drugs out there, often not exceeding 10% in purity, the rest being toxic byproducts, caffeine and other cuts which make the high very antsy, jittery and give you a horrible crash. If possible, take dexamphetamine. It serves its purpose as an anti-depressant way better than speed ever will.
Interesting,i use paste for two years with no problems.
Maybe its pure here,,my drug of choic would be adderall or dexedrine but there is no perscripton stimulants in my country so i need to take street amphetamine
 
Stimulants can indeed have antidepressive and even anxiolytic effects in therapeutic effects. Sometimes is less more, and one has to be aware that stimulants can be very addictive and lead to compulsive and manic behaviour. This risk increases with the dose. I would recommend dextroamphetamine as the levorotary enantiomer (speed is usually racemic) has primarily peripheric, adrenergic effects contributing little to the therapeutic but to the side effects.

It's a pity that we don't have triple transporter inverse agonists out there yet. as seen with the old MAOI antidepressives are compounds which affect all the big three transmitters sometimes superior, specially in therapy resistant depression cases. I think the reason why they failed in trials is because they were using triple transporter blockers (aka reutpake inhibitors, like in SSRI) vs. releasers (like amphetamines) or specially transporter inverse agonissts (like methylphenidate, cocaine). Reuptake inhibitors cause an initial delay period as it's seen with S/NRIs while inverse agonists work instantly by circumventing autoreceptors which downregulate the output of their relative transporter. But, of course, would triple inverse agonists have a seriously addictive edge.

Did you think about giving ketamine a shot? It's very effective at relieving depression for some and doesn't need to be dosed daily so much less risk of addiction. Unfortunately it has prohibitive costs in some places.
 
Will try tnx.
Just tell me what to expect i never used ketamine

It’s a dissociative meaning you lose connection with your mind and body. Low doses though are easy to handle and will provide the antidepressant effect. Its main effect lasts about an hour roughly. The antidepressant effects last about a week.

I highly suggest reading around on here about it.

-GC
 
It's garbage. Speed paste is only worth it when you wash it at least 3x with acetone and even then it makes you feel wired due to the levo component. It's perhaps one of the most cut drugs out there, often not exceeding 10% in purity, the rest being toxic byproducts, caffeine and other cuts which make the high very antsy, jittery and give you a horrible crash. If possible, take dexamphetamine. It serves its purpose as an anti-depressant way better than speed ever will.
Im on speed synce 3 weeks ago. Im trying to snort only 3-4 lines per day. I feel good with these shit. I try to shoot it and it does nothing. Is an strange thing. Do you know why? Today I'm not working and my parents are out so I'm drugged more than the others days.when I work I only take one line before going. Now Im trying lyrica and benzos.
Só I make a tRIPLECOMBO that work fine.
You are speedy but with a high sedation. Tomorrow I'm working so I want to be sleep at max.1pm
 
Im on speed synce 3 weeks ago. Im trying to snort only 3-4 lines per day. I feel good with these shit. I try to shoot it and it does nothing. Is an strange thing. Do you know why? Today I'm not working and my parents are out so I'm drugged more than the others days.when I work I only take one line before going. Now Im trying lyrica and benzos.
Só I make a tRIPLECOMBO that work fine.
You are speedy but with a high sedation. Tomorrow I'm working so I want to be sleep at max.1pm
First of all, using stims and downers is not safer use and secondly: don't ever shoot street speed.
 
Have tour done acetone wash? I never did it...could you explain me please? Or tell me another thing that can work? I only shooted speed one or two times
Thanks four your reply!!😈

Los of 💜 to drug users
 
WWII studies by allies revealed adding d-amphetamine to morphine sulphate significantly increased the analgesic properties.

Desoxyn, Desbutal, Dexamyl all amazing antidepressant

Methylphenidate (Ritalin) gave me amazing antidepressant effects when I started ….sadly, the euphoria fades. People always badmouth Ritalin, but it’s an inverse against nearly identical to Cocaine and is more potent than Cocaine. IV Ritalin (proper Pharma glass vials of pure powder) is a heavy hitter

Methylphenidate & Phenmetrazine are extremely euphoric antidepressants

Oxycodone was the best antidepressant I’ve ever taken…..I would formulate a special cocktail.

Dexedrine or Ritalin
Oxycodone IR
Diazepam

Oxycodone was the first drug to give me true euphoria. The second was one of the classic amphetamines…..Methylphenidate (Ritalin). Why do I feel so happy and outgoing? Why does it feel like my brain is cumming with dopaminergic euphoric bliss ?
 
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I am 25 years old male,,i was depressed,anxious,ocd,bod,adhd since i can remember.
When i was 12 years old i was diagnosed depression and medicated,,im these 13 years i tried all sati,snri,trycilic,tetracyclyc,atypical antidepressant,,i was also prescribed few antypsihotics,,mood stabilizers and a lot of benzos.
Notthing helped,,i got tms and finally ect and it helped a little for a while.
I was suicidal,lazy,unmotivated...and then one day my ex gave me dexedrine,,that changed everything i was completley depression free,,iz calmed my mind etc.
I tried everystimulant that exist and they all work very well.
Unfortunetly in my conuntry there is no medication for adhd so i need to self medicated with amphetamine paste.
Any explanation why stims make me symptom free,,,and i appreciate all comments on harm reduction related to amphetamine paste.
Tnx much love
Hi honey,

Will you do me a favor and please tell me the meaning of the following:

bod -- sati -- anri -- tms -- & ect.

I have some experience, but when it comes to the acronyms, I am a total idiot. Thank you for obliging.

And from everything I have experienced in 30 years, personally and from associating with others in a state that is like what you describe, it would be normal for a stimulant to bring the best relief or "feel good" condition you've found than from other chemicals, or even lifestyle changes.

I am in the U.S. and I have never heard of amphetamine paste. Then again, for such an intelligent, highly educated woman who understands many things, I have no shame admitting that I do not have any understanding, experience, nor formal education on most topics on this board. I actually like this and I am happy at the respect I have for the people and knowledge that this board contains. I think it is a very positive and helpful resource.

Your best outcome and positive thoughts are being sent your way.

V
 
WWII studies by allies revealed adding d-amphetamine to morphine sulphate significantly increased the analgesic properties.
Not just analgesic, they also increase euphoric properties when taken together. Once I got a prescription for methadone and methylphenidate which was among the most euphoric drug experiences and certainly the most euphoric prescription. Didn't take it for too long though, so I can't tell about how bad tolerance grows over time. Also I don't remember why I stopped it, I don't think it was due to side effects.

bod -- sati -- anri -- tms -- & ect.
Different groups of antidepressants. SSRI is selective serotonin reuptake inhibitor, like Prozac/fluoxetine. SNRI is serotonin norepinephrine reuptake inhibitor like venlafaxine. TCA tricyclic antidepressant. Tetracyclics are like mirtazapine.
 
Not just analgesic, they also increase euphoric properties when taken together. Once I got a prescription for methadone and methylphenidate which was among the most euphoric drug experiences and certainly the most euphoric prescription. Didn't take it for too long though, so I can't tell about how bad tolerance grows over time. Also I don't remember why I stopped it, I don't think it was due to side effects.


Different groups of antidepressants. SSRI is selective serotonin reuptake inhibitor, like Prozac/fluoxetine. SNRI is serotonin norepinephrine reuptake inhibitor like venlafaxine. TCA tricyclic antidepressant. Tetracyclics are like mirtazapine.
thanks
 
Be careful with it - taking speed every day made me psychotic. I thought I could smell my own brain.
 
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