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Opioids Sufentanil Citrate Dosage

CashCrop

Greenlighter
Joined
Jul 4, 2010
Messages
9
What would be the recommended IV dosage for someone with 3 vials of 50mcg/mL of sufentanil citrate (Sufenta)? Each vial contains 1 mL, giving a total of 150mcg in 3 mL. Since it's made for IV, this is the ROA desired. The person taking the Sufenta does about 100 to 150 mg of Oxy per day, or substitutes it for other opiates available, such as fentanyl (IV'ed often), morphine, or hydromorph.

Any help would be greatly appreciated and if there are any other threads or links concerning Sufenta dosages, please please send my way. Thanks in an advance.
 
this has scary written all over it to me.

I IV that much oxy at one time, and even I'd be terrified to shoot sufentanil, which is stronger than fent.

but wait for someone who knows a little more about fentanyl than me. just PLEASE don't think you know and go shooting a whole rigs worth at once or something.
 
In the OR they give 12.5mcgs sufentanil to opioid naieve patients for anesthesia, but the patients are also on 100% O2 non-rebreathers, CPAP, or intubated.
I have heard MDs say it's "10 times more potent than fentanyl" but I'm not sure if that is correct. Please start with very small doses, like 5mcg. One can always do more, especially since it has such a short duration of action, but please be careful.
 
Thanks for the help. I'm really second guessing if I should try this, and I knew from the beginning I wouldn't try it unless I was sure of a safe dose. My issue is 1) it is in front of me 2) I have IV'ed 600mcg of fentanyl in a 10 minute period and felt next to nothing, except my wallet being stolen from under me.

I understand its not worth risking without a 100% knowledge that I'm going to be fine, but I know someone knows or knows where information about dosage for sufentanil is??? Also, I'm obviously not going to be intubated but what about having naloxone ready to go with an experienced friend to poke me. Would it conteract the sufentanil if something went terribly wrong?

This information has to be somewhere, right?
 
Is the risk worthwhile?

How euphoric is it? How long is the duration? Is there a rush?
 
I'm sorry, I just don't believe you IV'd 600mcg in 10 mins. thats the same as wearing a 100mcg patch for 6 hours.
 
2) I have IV'ed 600mcg of fentanyl in a 10 minute period and felt next to nothing

I'm sorry but that is a very high dose to be doing in one shot, and I'm finding it a little hard to believe that was the actual dose.

The duration is around an hour. The feeling is very similar to fentanyl which, I personally don't care for, IMHO not worth the risk.

However, if you are determined to use it please start under 10mcgs.
The actual "correct" dosage is meant for anesthesia purposes and depends on your weight, etc... You will not find a dose appropriate for purely analgesic use listed in PDRs.
 
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Thanks Tiu.

But I did not say in one shot. I'm not interested in whether the other person who replied believes me or not, but it is totally possible. 3 mL rig...using 100mcg/2mL vials. That comes out to 4 pokes in 10 minutes. Completely possible and happened, but that not the point. The point is it didn't give me a rush at all just slightly felt it and what to do with its derivative, sufentanil citrate. 10mcg sounds like a good start, I'll let you know Tiu. And if you have any other information about this drug, I'd love to here it as i'll be trying it tomorrow.
 
I understood you didn't do it in one shot, but you just didn't do 600mcg in 10 mins. since it lasts for about an hour, so in fact, you might as well have shot it all up at once.
 
You are a joke. Not only is that besides the point, but the fact that you are so positive with yourself shows how arrogant you are. Nobody is agreeing with you because its very possible and happened. Read my previous post for the exact method, and if you don't have anything to say about the actual question then quit replying.
 
I believe Tiu agreed with me.

yes, at times I can be arrogant.

if I'm wrong, kill me, but I just don't see it happening.
 
According to equivalency charts, shooting 600mcg of fentanyl is equivalent to 9mg of Hydromorphone IV or 120mg oral oxycodone, neither of which are near impossible levels.

Let's stop arguing about it being possible or not guys.
 
then I stand corrected sir.

thanks for that info, now if I could just get my hands on some....
 
Well, on a medical journal which can be found at
http://www.medscapex.com/viewarticle/719038_2
username: noregistrationplease
password: bugmenot

For post operative pain relief they administerd 0.3 mcg/kg (or 0.13636 mcg/lb). I believe this dose may have been calculated on patients with a lack of tolerance. DO NOT TAKE A RISK however and before you even dose to this amount try a quarter of the dose, than half, than 3/4 and so on. You can always have a chance to do more, you don't always have a chance to do less!!

This is the dose chart for post operative pain relief from the journal. I just put some average masses to easily see where you might be at.

Dosage Chart

mass(lb) sulfentanyl
120.........16.4mcg
130.........17.7mcg
140.........19.1mcg
150.........20.5mcg
160.........21.8mcg
170.........23.2mcg
180.........24.5mcg
190.........25.9mcg
200.........27.3mcg

On another journal I read they compared fentanyl and sufentanyl for anesthesia and the result was 2.32mcg/lb of sulfentanyl for unconsciousness on average, while it took 12.27mcg/lb of fentanyl for unconsciousness on average. Therefore I derive a (1 : 5.29) ratio of sulfentanyl to fentanyl.

So if you can assume that you can take around your average dose of fentanyl and divide it by about 5, and you will come up with a dose of sufentanyl that will be about just as effective. To start I would maybe divide my fentanyl dose by around 8 or 9 as to ensure that you do not overdose due to the cross-tolerance. There is a chance that if you take fentanyl a lot you may build a tolerance of the drug itself and your tolerance to fentanyl itself will be higher than your tolerance to all other opioid drugs. So if we add this information to the chart above we will be able to come up with an average comparison of doses

*using the (1:5.29) sufentanyl to fentanyl ratio


Dosage Chart

mass(lb) sulfentanyl......fentanyl
120............16.4mcg.....86.8mcg
130............17.7mcg.....93.6mcg
140............19.1mcg.....101.1mcg
150............20.5mcg.....108.4mcg
160............21.8mcg.....115.3mcg
170............23.2mcg.....122.7mcg
180............24.5mcg.....129.6mcg
190............25.9mcg.....137.0mcg
200............27.3mcg.....144.4mcg
 
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I know this reply is 2 years later and probably not even using this venue but i must say this...
I have been a heroin user for 2 decades and have IV Fentanyl and there is NO WAY you could have done 600 micrograms in 10 minutes, or even 1 hour..
 
i also disagree with you... wearing a 100 mcg patch for 6 hours is not the same, as that is slow release over time... this chap claims he shot up 600 mcg in a needle... he would be dead if he shot 100!!!!!!!!!!!!!
i know this because i have shot up fentanyl and the most i have ever tolerated in one shot, was 100 mcg. that took 2 weeks to get that way
 
?How the hell did you obtain that shit? Shooting that is extremely dangerous i have no idea how to even make a recommendation on dosage, just be really careful man.

just realized this thread is hella old....dang
 
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