Well, except that he was really clear that he has been treating with them for many years with an excellent outcome, and for purposes of this website, the Golden Goose - recovery. He is presenting you with a possible excellent outcome with a drug that is considered to be a Frontline necessary drug in every country on our planet. I understand treatment resistance, my middle name as actually Treatment Resistance, but you're asking what if’s and risking the exact outcome you say you want to avoid. No one is trying to persuade you take take them, they are only sharing their experience that for them APs have been a godsend for manic depression, anti-psychosis, major depression and/or anxiety. Sometimes they are used just to stabilize a temporary situation so you can treat with other less intrusive and gentler medications. You can't know the outcome until you and your doctors get a sense of what's going on with you medically. We're talking about insanely well educated and well practiced medical specialists here. I have a brain capacity of about 1percent compared to them. A lot of people suffer these diagnoses. It's like it's completely okay to be ADD but God forbid you have mania that can't be treated or talked about like ADD. In fact one of my therapists I albeit briefly talked with, let me know there are a lot of very high functioning highly capable and accomplished people who suffer manic depression. Think about this, Jimmy Hendrix was manic depressive, he was a genius, right? But he died very young at a time when manic depression and the behaviour it expresses was very poorly understood. And we know he died of a drug overdose. There are lots of Jimmy Hendrix' out there (way more than you think) (Kanye West f.e.) who take medication for psychosis or manic depression. There are a lot of people who treat manic depression with opiates and opioids or other drug classes, it's very dangerous, and opioid deaths are a very real thing. Turn on the news or Google it, it's still a major driver of premature death. I don't think anyone seriously suggesting that psychiatrists, who are extremely highly trained in the bio-physiology of how the different areas of the brain and neurotransmitters work to make it possible for our bodies to function, and to use forward and abstract thinking, don't know anything about mental illness, or have no one's best interest at heart. In fact it's the complete opposite. It's okay to go to a cardiologist to get medical treatment for your heart (an organ) but not okay to get medical treatment for your brain (an organ), whaaaat? Explain that to me real slow sir. Or you can get a rundown at your local roach motel, er religious center, er church. Are those roaches plugged in, sir? That rat's not turned on is it? So they can tell you it's not acceptable to get medical treatment for mental illness? What are we supposed to do with all the VETs who served and have debilitating brain and psychiatric damage from war? Give em a soup can attached to wires and tell them to suck it up? No thank you.