Benzos Equivalent Norflurazepam to Diazepam Dose and what is the avearage or mean elimination half-life, duration of effect?

[Cream Gravy?]

There are literally zero studies on this stuff.

Uhhh... just thought I'd chime in, there's plenty of info on norflurazepam. It's a metabolite of something like SIX medicinally used benzos, chiefly flurazepam and midazolam which have seen plenty of use.

This user likely didn't receive norflurazepam, or has an insane tolerance. I'm very benzo tolerant, both naturally and from use, and 10mg will knock me out cold for 12 hours if I want.

 

[packjamNL]

Just because it's half life might be that long, doesn't mean it's going to be effective as a benzo or thienodiazepine still attached to the GABA-A receptor for that long. It's already broken down into it's inactive metabolites that aren't going to be effective at doing much of anything. I've never seen Flurazepam available on the open market. I don't know how you would talk your doc into prescribing you this stuff. My shrink won't even prescribe me more than 15 1mg Xanax a month, so I'm stuck with 5mg Valium pills twice I day. I actually thought you were talking about the RC drug Flubromazolam which is very strong at very low doses, but I don't know what what the half life is, since it's an RC chem, there's a lack of studies on it.

I would LOVE to find phenazepam. I don't know if it's against the rules to ask for sources, so I sincerely apologize if I'm breaking the rules, but if you have any leads shoot me a PM.


I used to see nitrazepam on the markets, but I haven't seen it it in ages. I wish the fucking DEA didn't schedule Soma, as the only place to get it from is the UK (AFAIK) and SWIM got their package seized by Customs from trying to get ahold of it.

It was likely a super low dose & even if it wasn't gabaergics in general typically have very subtle hard to notice effects.

Norflurazepam begins to take effect at minimum dose of 5mg & for hypnotic effects it takes 10mg minimum but with daily dosing especially is when it really shines specifically for muscle relaxing effects or that euphoric type of hypnotic effect+anti-anxiety effect which last long time.

At daily dosing of currently 12.5mg(roughly) it lasts long enough to make really hard for to want to wake up until 24+ hours after my last dose.


The topic is equivalent doses which idk the equivalent doses or how long Flubromaze-PAM duraation of effects lasts compared to Norflurazepam but I do think from what I've read & considering it's a phenazepam analogue it has a way longer elimination half-life & is a way stronger hypnotic that will cause far harsher withdrawal.









@Vælte Peter What drug are you on & wtf are u talkin bout are you in the wrong thread lol?

When u say this I think u mean your the reckless type of drug abuser that gives us drug users a bad reputation. "I’m more like a ginniepig - in the way of if wouldn’t scale my molly and sit with a stop watch and my hand while rolling haha. Than rather take a bit too much. Rather that than too little. Besides from GBL - but that’s another story"

This thread is for talking about equivalent doses.

I did 1 gram in 200ml propyleneglycol, so 1 ml is 10 mg and or two pellets

 

[dorian.927]

Hello,

Yesterday night and a few days ago I tried Norflurazepam 4*5=20 mg in a single dose in the evening. My felt equivalence is about 4.5 mg norflurazepam = 10 mg diazepam. But this equivalence much surprises me as Delorazepam, the chlorine conterpart of flurazepam, is much more powerful by mg unit : 1.2 mg delorazepam = 10 mg diazepam according to my equivalency table sources of information. Though fluorine substituant is much more electronegative than chlorine substituant (juste check these two molecules on wikipedia). So, theoritically, Norflurazepam should be much more powerful by mg unit than Delorazepam.

Basing on these facts, is someone able to explain me why Norflurazepam is much less powerful by mg unit than excpected ?

Thank you in advance for your explanations.

Regards.

 

[packjamNL]

Norflurazepam is voor mij een ongeduldig ( ja Rohypnol is mijn 1e keus, maar hiel moeilijk aan de komen en dan heb je een generieke tablet ) ik ervaar het meer als een kalmeringsmiddel i.p.v. een slaapmiddel zoals andere benzodiazepinen. Het is te koop als poeder en dan likt het nog sterker te zijn, oplossing gemakakt 1 gram in 100 ml. in propyleenglycol. Ik weet niet alles van, maar het werkt i.i.g. euforisch, het is bijna dope, ik las dat het verdooft ook een bijje, en het tintelt op je tong. Wat ik vreemd vind dat pellets van 5 mg. weinig lijken te verschillen met blauwe 10 mg. in strips. Als je die strips omrekent en vergelijt met 1 gr. poeder, dan ben je een paar euro goedkoper uit, het verschil is duidelijk merkbaar als je 1 gram koopt met de 10 mg. tabletten. Jammer dat het duurder is geworden. Hoe dat komt kan verschillende oorzaken hebben.

 

[packjamNL]

Hello,

Yesterday night and a few days ago I tried Norflurazepam 4*5=20 mg in a single dose in the evening. My felt equivalence is about 4.5 mg norflurazepam = 10 mg diazepam. But this equivalence much surprises me as Delorazepam, the chlorine conterpart of flurazepam, is much more powerful by mg unit : 1.2 mg delorazepam = 10 mg diazepam according to my equivalency table sources of information. Though fluorine substituant is much more electronegative than chlorine substituant (juste check these two molecules on wikipedia). So, theoritically, Norflurazepam should be much more powerful by mg unit than Delorazepam.

Basing on these facts, is someone able to explain me why Norflurazepam is much less powerful by mg unit than excpected ?

Thank you in advance for your explanations.

Regards.

no, it's the standard of the vendor

 

[packjamNL]

Hello,

Yesterday night and a few days ago I tried Norflurazepam 4*5=20 mg in a single dose in the evening. My felt equivalence is about 4.5 mg norflurazepam = 10 mg diazepam. But this equivalence much surprises me as Delorazepam, the chlorine conterpart of flurazepam, is much more powerful by mg unit : 1.2 mg delorazepam = 10 mg diazepam according to my equivalency table sources of information. Though fluorine substituant is much more electronegative than chlorine substituant (juste check these two molecules on wikipedia). So, theoritically, Norflurazepam should be much more powerful by mg unit than Delorazepam.

Basing on these facts, is someone able to explain me why Norflurazepam is much less powerful by mg unit than excpected ?

Thank you in advance for your explanations.

Regards.

Did you buy powder of 5 or 10 mg pellets?

 

[packjamNL]

Hello,

Yesterday night and a few days ago I tried Norflurazepam 4*5=20 mg in a single dose in the evening. My felt equivalence is about 4.5 mg norflurazepam = 10 mg diazepam. But this equivalence much surprises me as Delorazepam, the chlorine conterpart of flurazepam, is much more powerful by mg unit : 1.2 mg delorazepam = 10 mg diazepam according to my equivalency table sources of information. Though fluorine substituant is much more electronegative than chlorine substituant (juste check these two molecules on wikipedia). So, theoritically, Norflurazepam should be much more powerful by mg unit than Delorazepam.

Basing on these facts, is someone able to explain me why Norflurazepam is much less powerful by mg unit than excpected ?

Thank you in advance for your explanations.

Regards.

Try to stay on flurazepam, I get Tranxène to kick the habit 2 x 50 mg ( 2 x 35mg diazepam) and it's poison, I read about acids and sulfur, it starts to hurt, I want Flurazepam from my specialist 120mg a day then 90 etc,

 

[kokaino]

Nitemazepam, the 7-nitro instead of 7-chloro of temazepam or the 3-hydroxy derivative of nimetazepam is probably the best benzo. My Chinese vendor said it got banned in China in 2022. It has several metabolites, one of which is temazepam and the other is nimetazepam, as well as a couple others. So I got a custom synthesis of Flutemazepam. I'll see what that's like.

I'm also surprised Nitrazolam never became a hit. It is way better than most of the designer benzos that the majority consume.

 

[packjamNL]

Hey everyone I am trying out this very interesting RC Benzodiazepine. It has a strong minty cool feeling in the mouth when drinking it in a PG Solution, it has several active metabolites with 40 to 250 Hour Elimination Half-Life.

I read the prescribed Benzo Flurazepam is a pro-drug that turns into N-Desalkylflurazepam A.K.A. Norflurazepam which is responsible for its effects... this means that Flurazepam = Norflurazepam only difference is the potency in weight per mg correct me if I'm wrong about this?

If that's correct then the only difference is the equivalent dose. I read that it can have up 250 Hours half-life in the elderly and people with impaired kidney and or liver function but for the young healthy adult the average or mean half-life is usually around 90 Hours for Flurazepam at least I think I remember reading an article saying that.

If anyone could please help me figure out at the equivalent dose to Diazepam specifically. I need an educated guess about the equivalent dose for use in consecutive days and acute doses if possible. This has some of the best muscle relaxing properties alongside the best insomnia relief I've come across in any benzo with the benefit of lasting a long time and providing anxiety relief into the next morning.

 

[packjamNL]

Nitemazepam, the 7-nitro instead of 7-chloro of temazepam or the 3-hydroxy derivative of nimetazepam is probably the best benzo. My Chinese vendor said it got banned in China in 2022. It has several metabolites, one of which is temazepam and the other is nimetazepam, as well as a couple others. So I got a custom synthesis of Flutemazepam. I'll see what that's like.

I'm also surprised Nitrazolam never became a hit. It is way better than most of the designer benzos that the majority consume.

Nitrazolam is made by Cayman Chemical https://cdn.caymanchem.com/cdn/insert/22620.pdf and I found this https://pubchem.ncbi.nlm.nih.gov/compound/Nitrazolam, I also find it on sites that sell the more known benzo's like Diazepam or Clonazepam (Which is my favorite)

 

[packjamNL]

Diazepam has a half-life of up to 200 hours because of it's metabolite desmethyldiazepam. So I think the comparative value is for any kind of dosing.

My specialist told me that I never gonna be able to leave benzo's behind in my life, I am atm on Tranxène 2 x 50 mg which is equal to 2 x 35 = 70mg Diazepam. I will tell her soon that I want Flurazepam 90 or 120 mg a day, and lower it to 30mg a day

 

[notrandomusername]

I'm also surprised Nitrazolam never became a hit. It is way better than most of the designer benzos that the majority consume.

Nitrazolam was available as an rc for years. Afaik first released by a few uk vendors, just before the uk ban. After carried in powder form by some nl vendors.

Probably never became a hit because at that point in time clonazolam/flualprazolam/flubromazolam were also legal and the price/g was roughly the same for all.

Just like bromazolam didn't become a hit until those 3 were banned.

But yes, I personally prefer nitrazolam over bromazolam too.

 

[kokaino]

I still know a Canadian vendor that sells Nitrazolam 10mg/ml solution. I think it's a great benzo. However, I was referring to Nitemazepam

 

[notrandomusername]

I still know a Canadian vendor that sells Nitrazolam 10mg/ml solution. I think it's a great benzo. However, I was referring to Nitemazepam

Never tried nitemazepam (I think I saw it on some Chinese site years ago?), although I imagine it should feel pretty good.

I think it's problem would be that it's likely not very potent so if rc vendors can synth and sell things with a higher potency that people still buy, they are going to go for the ones that bring the most profit not necessarily the ones that are the most enjoyable. That's how we got to clonazolam and related compounds.

 

[kokaino]

@StarScream66 Norflurazepam is actually a active metabolite of A LOT of different benzos it's just that Flurazepam produces the most and all of its effects are from norflurazepam. I had flurazepam prescribed for insomnia but I got my Dr. to switch my to Nitrazepam since I was able to simply buy norflurazepam.


I'm hesitant to switch from 10mg nitrazepam to 30mg flurazepam as unfortunately I've read it's only a partial agonist meaning switching would be a bit unpleasant. If I switch I can get nitrazepam but just not at as cheap of a price as norflurazepam.

DON'T DO IT! 10 mg is superior to 30 mg flurazepam. However, flurazepam is indeed a full agonist BZD. Full stop! Anything you read about partial agonism is bullcrap.