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Gabapentinoids Phenibut and Etizolam cross tolerance?

M

menidiatis

Bluelighter
Joined
Jul 24, 2021
Messages
479
I remember reading that Benzos work on GABA a while Gabapentinoids work on GABA b receptor.

Is it then still possible that they have cross tolerance? Or could I use 2 weeks etizolam and then 2 weeks phenibut so that tolerance is reset every time?

I d really appreciate answers from people with real life experience with this experiment
 
I find very little cross tolerance. I've had a ~4g/day phenibut habit for years, but I can still feel 1mg of etizolam. Phenibut does eventually activate GABA-A but not at the benzodiazepine binding site.

However I would strongly discourage taking either for 2 weeks at a time. This is a formula that will likely lead to significant misery/suffering in the future.
 
I haven't found a cross tolerance between the two personally.
I haven't found a cross tolerance between phenibut and anything else come to think of it.
As posted above: Either party for two weeks and drop it or dose every third day or no more than twice a week to stay away from hells gates.
Just realized that I didn't dose phenibut today. Didn't seem to be an issue that I recognized. I used to dose every third day and went to every other day about 6 months ago. Maybe I will get back to that every third day dosing regimen.
My bad some tangent thought kinda off topic.
 
I either drink 3 liters beer every day, take 0.75 - 1.5mg of etizolam, or smoke 1 g if unknown purity heroin (but strong for sure). I try to alternate between them as often as possible, so that I don't get physically hooked since my emotional dependence in downers is already there.

If I don't do that I get severe panic attacks and honestly I d rather be hooked on drugs than have to deal with that.

I hope within 6 months to eradicate my remaining social anxiety so I can get a gf and drop all drugs once and for all.

Meanwhile an extra addition of something to have 4 instead of 3 things to rotate would be useful
 
menidiatis said:
I hope within 6 months to eradicate my remaining social anxiety so I can get a gf and drop all drugs once and for all.
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It would seem that dealing with the core of the anxiety would better suit this need than "painting" over it with substances.
I am going through a bunch of crap atm and feel that drugs will save me from it all but know from past experience that this will only makes things more difficult when it's time to pay that piper.
I have a ton of anxiety but it's not in a social situation... mine is based on balancing a home life cause if I slip lots of damage can be done. I have a lot on my plate and I have to eat it all. On top of this for 26 years I feel like I have been used as a mule of sorts... just to carry the burden now my mind is playin tricks on me and I gotta sort this out.
Maybe you could school me on this; you write "remaining social anxiety"... was there previously more and how did you get past the greater part of it.
Seriously curious and open to any perspective.
 
First of all I am sorry to hear you are going through such troubles. It seems some of us have been screwed harder by life and that's why we have ended up on heavy narcs.

I had very severe social anxiety, I could not even exit my student room to go to the bathroom to pee, let alone go to super market for groceries or school for class. I overcame it (after self diagnosing it because I have an affinity for psychology) following a CBT program designed for that. It took me 3 years, and I am still doing this. But now I am not a cripple, I am fully functional, I just have a hard time with girls which really makes me suffer as I crave a partner really badly and can confidently say I would not be doing heavy drugs had I had a gf.

My suggestion if you suffer from mental illness is to find a competent psychologist to guide you through a CBT program, which is the best form of therapy for anxiety disorders. Please find a competent one who specialists in treating people with anxiety. There are boatloads of crap psychs so this might be hard. The help of a professional is the fastest way to deal with psychiatric disorders imo. Let me know if you have any questions I ll gladly help!
 
menidiatis said:
if you suffer from mental illness is to find a competent psychologist
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been seeing them since a youngin and they all give me the stamp of "normal". Now mid 50s and just know that life brings more the older we get if we actually gaf about anything.
I guess one could argue that I am depressded or otherwise but life is what it is... I self medicate to try to keep up and doing fairly well with it. Just getting to see too much behind the curtain and not liking what I have been seeing. Not the end by far or by any means.
menidiatis said:
First of all I am sorry to hear you are going through such troubles. It seems some of us have been screwed harder by life and that's why we have ended up on heavy narcs.
Click to expand...
Agreed. From mental to physical sufferings. We all have them I am not special in this. I know. I stay on the lighter side of the narcs now as I see they have caused more harm in the past and can drop them a lot easier than the "good" stuff".
menidiatis said:
I am fully functional, I just have a hard time with girls which really makes me suffer as I crave a partner really badly and can confidently say I would not be doing heavy drugs had I had a gf.
Click to expand...
In my experiences this finding a gf could make a mf go from snorting coke to shooting H. I hope ya find the right one as I did... even though it may be coming to the end of our "togetherness" I also know that there is something to be learned from it, I have learned a lot, we grew together but now looking like it was all illusion. The things we "grew" and learned from each other will remain.
I give here a lot of credit for pulling me out of a self-dug grave but to be perfectly honest? I would have to say that this website has done more for my well being in a coupla three years than decades of other influences.
Just keep trying is all I can do.
Nothing stand-outish in my situation just time, chance and opportunity kept me alive. To be fair she has "woke me up" twice when I was at my worst. BL has kept me from going back to those darkest of places. I would like to say that I give BL (it's people) too much credit but I wont and cant cause I know what I know.
 
menidiatis said:
I either drink 3 liters beer every day, take 0.75 - 1.5mg of etizolam, or smoke 1 g if unknown purity heroin (but strong for sure). I try to alternate between them as often as possible, so that I don't get physically hooked since my emotional dependence in downers is already there.

If I don't do that I get severe panic attacks and honestly I d rather be hooked on drugs than have to deal with that.

I hope within 6 months to eradicate my remaining social anxiety so I can get a gf and drop all drugs once and for all.

Meanwhile an extra addition of something to have 4 instead of 3 things to rotate would be useful
Click to expand...
Hi, have the same prob, would like to chat with you
 
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