@Survived Abortion, thank you for posting all that stuff, that is very interesting indeed.
Could you elaborate which side effects you mean? Bladder feelings? Or urinary retention, perhaps? Is it supposed to counter the actual damage in some way...? Or just the feelings?
Just curious as I had a somewhat harebrained idea a while back to drink diuretics while I was doing ketamine such as caffeine, or beer, to potentially empty my bladder more often and thus protect against damage. I felt at the time that maybe it helped but in retrospect this was probably just placebo.
Anyway personally now I always find beer ruins that lucid psychedelic edge I like to feel when doing ketamine, but it probably would help with urinary retention.
For alcohol, I don't think it's a great idea which is why I didn't go into it. It's certainly not a wise combo and has led to many deaths due to risk of vomiting. But there does seem to be something about it in small quantities to hydrate and also break down the ketamine so it passes easier. I would not be using it throughout the binge to help piss. Agree it also kills the experience.
I find infrequent doses of coffee, decaffeinated tea and the occasional yogurt/pro-biotic drink sit better with me than alcohol. Cranberry is also good in very small amounts, big amounts cause kidney stress if taking ketamine at the same time for me. Magnesium helps prior-to/tail-end/post binge.
You can khole standing up and move around. I wouldn't say you'd pee in a hole - I've never wet myself on ketamine but many others do when mixing with alcohol and low tolerance. I find you can nearly go in and out of holes like a tightrope if you use sensory deprivation and music too.
If you need to go to the toilet you'll easily snap out of the hole in 10-15 mins max and be able to go. A redose shortly after induces the hole for me again. If I can comfortably sit down in a hole I will, but if I can't I can stand and just not move. Some of my most intense k holes have been standing frozen at a rave and much more visual. Although if you IM .5-1g with no tolerance you're going down due to anesthetize/blackout and will possibly hit your head on the way down.
I never found much benefit going above 200-300mg on IM ketamine within a single dose time frame. It causes arrhythmia and other discomforts. Insufflated you can sniff grams but it just causes unnecessary tolerance and damage - I miss the cheap ketamine of that time but not the 'party' abuse. 2c roulette and heroic acid doses were much safer.
Any lectures on bladder damage tends to refer to ketamine irritating the lining, I imagine this is due to dehydration and the ketamine itself recrystallizing. I've never found a fix for good ketamine being 'dry' other than using atleast 1ml/80-100mg and keeping hydrated. The rocky batches are particularly harsh and need more water.
Cooking k also makes it easier on the nose which helps it absorb/passes better. As does crushing. It should go to a flour consistency. Doing either and staying hydrated works wonders for a one off. Supplementing in other ways makes a big difference for habitual use. I'm not a fan of vanilla essence for the same effect, it hurts the kidneys.
I found the hole on MXE even more functional at massive doses. O-PCE/MXPr completely knocked me down.