- Jul 29, 2004
- that rainy little island off europe
hussness said:^Wouldn't that be a potential alkylator?
A halogen (not fluorine) on a benzyl carbon - generally they are really reactive and will alkylate just about any amine they come across and as it potentially only takes one error (in the right place) in DNA replication to initiate all sorts of shit to occur, it looks like a reject in the risk assessment department.
Things like dry mouth, sweating even occasional heartburn are all acceptable (unless very severe) side effects for a drug if it seems what you get out of it are worth it to you. No drug is worth the potential crap that would inevitably occur with prolonged exposure to DNA alkylators unless they are the cytotoxic chosen to treat a caner that's already present