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Sexual dysfunction using baking soda with dexamphetamine

nuffybus

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Wondering if anyone has experienced sexual dysfunction using dexamphetamine and baking soda together? Previously no problems until the baking soda was added in. If so what would the reason be?
Appreciate your feedback..
 

Nicomorphinist

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Baking soda as an antacid with oral dextroamphetamine to make it last longer, or using the baking soda to cook it into rocks and smoke it?

One possible cause for not getting or keeping it up is low and/or labile/rapidly changing blood pressure, which may or may not be relevant here. The only time I can remember anything like that was a 40°C + day like today when dehydration had a lot to do with it. Buy some Pfizer stock and physical Viagra with your carbon credits is the investment advice of 2030 I am sure.

Other drugs-related dysfunction could come from reduction in feeling in ones Tower of Power for whatever reason, but I would think that some of the others which are caused by modified hormone levels would take weeks to years to develop and be more subtle at first then a real bitch to fix . . .
 

Zonxx

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Baking soda as an antacid with oral dextroamphetamine to make it last longer, or using the baking soda to cook it into rocks and smoke it?

One possible cause for not getting or keeping it up is low and/or labile/rapidly changing blood pressure, which may or may not be relevant here. The only time I can remember anything like that was a 40°C + day like today when dehydration had a lot to do with it. Buy some Pfizer stock and physical Viagra with your carbon credits is the investment advice of 2030 I am sure.

Other drugs-related dysfunction could come from reduction in feeling in ones Tower of Power for whatever reason, but I would think that some of the others which are caused by modified hormone levels would take weeks to years to develop and be more subtle at first then a real bitch to fix . . .
this is not a question related to the thread/topic at hand but one about your post pertaining to hormone levels altered by drug use over time, Opiates are said to do this but i never neccesarily researched the topic so maybe you can give me a solid answer, how long does it take to develop issues related to hormonal changes caused by opioid use?
aswell as do the hormone levels bounce back after cessation of use?

this has been one of my concerns that i've put off looking into because i can't have too many worries about my drug use that i'm dependent on to get through the day
 

nuffybus

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Baking soda as an antacid with oral dextroamphetamine to make it last longer, or using the baking soda to cook it into rocks and smoke it?

One possible cause for not getting or keeping it up is low and/or labile/rapidly changing blood pressure, which may or may not be relevant here. The only time I can remember anything like that was a 40°C + day like today when dehydration had a lot to do with it. Buy some Pfizer stock and physical Viagra with your carbon credits is the investment advice of 2030 I am sure.

Other drugs-related dysfunction could come from reduction in feeling in ones Tower of Power for whatever reason, but I would think that some of the others which are caused by modified hormone levels would take weeks to years to develop and be more subtle at first then a real bitch to fix . . .

No just adding baking soda to the dexamphetamine to make it more effective. Usually take it 30-60 mins before the dexies..
 

nuffybus

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No just adding baking soda to the dexamphetamine to make it last longer. We take the baking soda 30-60 mins before dropping the dexies..
 

Nicomorphinist

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The lore and some scientific findings are concerning hypogonadism which seems to be associated with high-dose use over years, and there seems to be a stronger effect wrought by open-chain opioids like methadone than is the case with morphine derivatives and others. It can happen, but there are also people to whom it does not happen, and when it does happen, it seems to resolve rapidly when the drug is discontinued or reduced, and the effects appear to all be well-known ones which can be prevented and managed quite easily.

Hypogonadism is the usual thing for which they keep out an eye in cases like this -- two chronic effects of lowered free and conjugated sex hormones can be osteoporosis in both men and women (get lots of phosphorous, calcium, Vitamin D and make sure to walk at least a little each day -- I've added in magnesium and strontium supplements and had good results) and sex-linked effects like erectile dysfunction and amenorrhoea. The hormone levels and reduced blood pressure can both contribute to the former. The doctors treating me for chronic pain have done bone density scans on me every seven years for quite a long time and started with a baseline whole-body x-ray when I started all those years ago.

Exactly how premature ejaculation works into all of this is a bit confusing; one does hear about it . . . note also that a Stage IV narcotic withdrawal symptom in men can be hair-trigger painful orgasms requiring no erection at all, so maybe that all is related and it is related to the hydraulics of the whole thing.

I would also point out, using morphine as the most common, well-known, and longest-researched example, that taking it will lead to increased libido at moderate doses, then higher ones could reduce it as the contentedness and euphoria is already there and not requiring the endorphin and acetylcholine blast from an orgasm, and the interest may not be as intense, therefore adding the subjective element to anything the actual hormone levels and their effects are causing.

For men, the use of the topical testosterone gel that is rubbed on the upper arm seems to be a very good way to prevent or counteract this, and monitoring of free testosterone levels should be part of the regular testing done at least annually in chronic pain patients, as there are actually is a wide array of bodily changes which can take place. Other herbal and prescription supplements seem to have good effects for people; the combination needs to be put together by a physician and monitored to make sure nothing additional is going to get started or is being masked.

There is papaverine for intracavernous injection into the whanger to treat erectile dysfunction, but it may not be that complicated: I have never had a problem with it and I make sure to have whole opium in some form several times a week so that the papaverine, and morphine, codeine, noscapine, narcotine, and everything else is floating around -- no need to stick a needle in my cock or wait for Viagra or Cialis and risk a week-long hard-on.

The analogous metabolic, endocrine, and reproductive effects in women can and do occur for the exact same reasons of course, with enhanced osteoporosis risk being the big one. I have never heard of women growing beards from narcotics or anything else for that reason.

I have not heard anything about how this, or other drugs like amphetamines, benzodiazepines or other things, could affect hormone levels and therefore the above-mentioned parts of health and related matters in the case of intersex, trans, transitioning, transitioning back or non-binary people or the like.

I did know a long-term dipipanone chronic pain patient who had more trouble with osteoporosis than the doctors would have otherwise expected, though there was no way to know for sure, I suppose. There are people on dextromoramide, propoxyphene, and other open chain opioids who didn't seem to have trouble with anything like this. Then again, the people I knew whose narcotic use careers were in the 55 to 102-year range reported no trouble with that kind of thing at all and looked younger than their years. One person I know who has been on piritramide since the month it went on the market says it makes her horny. I have also heard about pethidine, piminodine, anileridine, and alphaprodine turning people into fuck bunnies as an indirect effect of the neurotoxicity in the patients' own estimation. Must be why alphaprodine was mainly used as an obstetric analgesic which lasted for 60 minutes.

Apparently this is all somewhat dose related, and some recovery can begin to show up later during the first week of cessation. There seems to be no reason to assume permanent changes take place, and this all is suspected to be much of why some men on narcotics have trouble getting it up but also may not be as interested in the first place, and why some women have traditionally used opium, morphine, heroin, and so forth as a second-line crude form of birth control.
 
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Nicomorphinist

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No just adding baking soda to the dexamphetamine to make it last longer. We take the baking soda 30-60 mins before dropping the dexies..

So then it would really be whether the baking soda had that effect, and I have never heard of it, and also the increase in the dextroamphetamine effect, which seems to me is simply making it work better and longer by raising the serum level and smoothing the curve, so it could be something totally unrelated and co-incidental, or a complete fluke . . .
 

d1nach

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I believe:
baking soda is sodium bicarbonate which is a base because it can "neutralize" acids and therefore raise the ph of acidic solutions.

The ph of the stomach and urine is alkaline it may influence the absorbsion and elimination of amphetamine.

Therefore, i think the reason your experiencing erectile dysfunction with baking soda but not without is due to higher levels of amphetamine.

Ie
Baking + no amph = no erectile dysfunction
Amph + baking soda = ED
Amph + additional amph = ED

However this is a guess.
 

Nicomorphinist

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Can the amphetamine be enough of a smooth muscle relaxant to allow the blood pressure in the Blue Veined Custard Chucker to not rise high enough to keep the erection going? Although I never had any cock issues with White Crosses, one effect I remember of them was the curious change in blood pressure from my normal baseline of 95/60 to 135/40, and other folks have mentioned the fall in diastolic pressure too.

(think pseudoephedrine or ephedrine and the like, and oxymetazoline and so on -- or pre-1930s, amphetamines -- for stuffy nose)

Yet, the laevorotary amphetamines also have the decongestant effect, hence the OTC inhalers of levomethyldesoxyephedrine -- or, that is, levomethamphetamine, or Crank minus the Shabu -- in the USA and other places.

Then I hear all these tales from folks who like Party & Play and going at it, even in Daisy Chains, for 12 hours or more . . . I do know there are different levels of circulatory effects of amphetamine, dextroamphetamine, methamphetamine, dextromethamphetamine and so forth, much of the reason they were originally approved for different things.
 
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Jack123456

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Can the amphetamine be enough of a smooth muscle relaxant to allow the blood pressure in the Blue Veined Custard Chucker to not rise high enough to keep the erection going?

That's not how erection works. The erection is caused by parasympathic relaxation which leads to increased blood flow into the penis (arterial dilation and pressure on surrounding tissue is also inhibiting venous reflow), while ejaculation is due to sympathic activity.
 

Nicomorphinist

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That's not how erection works. The erection is caused by parasympathic relaxation which leads to increased blood flow into the penis (arterial dilation and pressure on surrounding tissue is also inhibiting venous reflow), while ejaculation is due to sympathic activity.
Can we clear the dextroamphetamine from suspicion then? It may be a fluke that was caused by something unrelated . . .
 

Jack123456

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Can we clear the dextroamphetamine from suspicion then? It may be a fluke that was caused by something unrelated . . .

Not really, a quick google search shows that is has been linked to erectile dysfunction.

Just for caution: Countering stimulant induced ED with viagra is dangerous and unsafe (just to mention it, should desperation lead to this idea :) )
 

Nicomorphinist

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Not really, a quick google search shows that is has been linked to erectile dysfunction.

Just for caution: Countering stimulant induced ED with viagra is dangerous and unsafe (just to mention it, should desperation lead to this idea :) )

Viagra started out as a blood pressure or heart medication, and I am surprised that in the cases where people have tried to use it IV that there were not much more serious problems in the end. The viagra plus speed or cocaine given unawares to someone as a murder weapon is a rather common plot element on police procedural and medical drama shows these days too, I have noticed.

Also, with the possibility of serotonin syndrome, people should not try to counter negative stimulant sexual effects with tramadol or tapentadol, or other drugs such as some antidepressants or smoking cessation aids sometimes used like this too. Most assuredly not all three categories at the same time!

If the neurotransmitter levels have a lot to do with the ED, I suppose they could be attenuated with conservative dosing of the same kind of antihistamines and related drugs used for migraines and mild to moderate serotonin syndrome, cyproheptadine and phenindamine, as well as hydroxyzine, meclizine, buclizine or cyclizine but especially the hydroxyzine, and perhaps members of other categories . . .

I am thinking if there is anything safe to try to filter out the ED effect that may be coming from dextroamphetamine, it is

1. Less dextroamphetamine
2. Time
3. Maybe poppy pod or seed tea, paregoric or laudanum, or a small amount of Op if it can be had -- there is the morphine and codeine to counter the effects, and papaverine to work on the ED directly -- I can report that it need not be shot into the cock to work, and I do hear stories of a pleasant tingling, pulsing, and change in size and colour of the clitoris as well . . .

Dibs on the idea of a capsule, syrup, or tablet for these cases of precipitated ED which is basically Diconal with papaverine added to it!

I have heard people speak of "coke dick" from taking lots of Bolivian Marching Powder, but I have not actually come across a coherent consensus on what it actually is . . . and then more than once about priapism being an after-effect of a crack or White Tornado session with really good C-Jam and/or crack . . .
 
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Derschieber

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Does baking soda really make a significant (obviously noticeable) difference to the effects of amphetamine? I mean besides the suspected ED reported by the OP.
In my personal experience, Speed, Meth & Dex can have radical effects on my sexuality and function, not all the time or always in the same way. Unpredictable if nothing else.
 

Nicomorphinist

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Does baking soda really make a significant (obviously noticeable) difference to the effects of amphetamine? I mean besides the suspected ED reported by the OP.
In my personal experience, Speed, Meth & Dex can have radical effects on my sexuality and function, not all the time or always in the same way. Unpredictable if nothing else.

The baking soda changes the systemic pH and can therefore have an effect on all five parts of the Liberation, Absorption, Distribution, Metabolism & Elimination profile, with the result that it lasts longer, and the comedown is less steep than it would be otherwise . . . this can happen with a lot of drugs, often like this, some times in reverse . . . the really commonly-known ones are the amphetamines and ephedrine, as well as people who make their methadone, levomethadone, dipipanone, phenadoxone, or dextropropoxyphene last longer with antacids, or have it clear out of their system more quickly with Vitamin C, vinegar, and things like that.

Something which is of roughly the same store are the folks who have the lime or ash container which they use with their coca leaves and betel nuts to get the ingredients into a more easily-absorbed form and maybe some other advantages.

The antacid, acid reducer, grapefruit juice, and any Vitamin C and/or calcium, magnesium &c effects on hydrocodone, oxycodone, dihydrocodeine, nicocodeine, and codeine are more complex, more subtle, and more subject to debate. The effect of cimetidine and the like on hydrocodone and oxycodone duration and intensity seem to be the impact of a couple of the isoforms of Cytochrome P-450 rather than the pH of the digestive system and other systems down the line, the bladder included. Tramadol is an even more complex one.

There is apparently a technique used by doctors in the early XX. Century and described in the 1913 edition of the Lippincott medical and surgery textbook and reference where they added magnesium sulphate to the saline used to dissolve morphine which would cause it to last 19-25 hours after an intramuscular injection, and there is some debate that other routes would also benefit, but I have not seen this reproduced. Lately, the word on the street about super long lasting morphine is of a liposome formulation a pharmaceutical company is working on which can be used to make boluses lasting 7 to 10 days, generally in the arse cheek. Which is where I prefer my shots of atropine myself.
 
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Derschieber

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@Nicomorphinist I appreciate your informative reply. Thank you.
The average drug user, who may not be so well informed about the why or how...the guy (for example) who simply takes some baking soda because he's heard about how this will prolong the effects - do you think he will really notice an obvious difference?
 

Nicomorphinist

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@Nicomorphinist I appreciate your informative reply. Thank you.
The average drug user, who may not be so well informed about the why or how...the guy (for example) who simply takes some baking soda because he's heard about how this will prolong the effects - do you think he will really notice an obvious difference?

With amphetamines it can actually be pretty noticeable, and I believe there may actually be an ephedrine formulation for wakefulness which has a carbonate or bicarbonate of some type in it, for this reason. The effect with methylphenidate, phenmetrazine, phendimetrazine, and some of the others seems to be more subject to debate, and I have heard of Captagon fanciers who make sure that there is at least some Maalox or Tums around.

It is so uncommon to swallow C-Jam, (though I like to purify it and stir it into Coca-Cola to get the old 1888 recipe for Cherry Coke) that I have not heard anything about this with that -- but of course Bolivian Marching Powder plus baking soda cooked up turns into crack, which can be done with caffeine and other things too . . . I first heard about caffeine being cooked into rocks by a community activist who was pointing out the racism of anti-Crack laws (the differential in sentences and so forth) right after the laws were passed . .. I think the group was Acorn, and I brought it up at an NAACP meeting later the same week . . .

Chewing coca leaves is often done with an alkali mixed with the leaves into a wad which is chewed and moved around the mouth over several hours.

When I mentioned the caffeine cooking to some folks, a glassblower from Prague who has a wife who is a pharmacologist gathered about ten of us together and we tried about three dozen different things to see if they could be cooked into rocks -- I made a caffeine and nicomorphine rock which was like the Moon Rock of crack and heroin base that are common some places. Some compounds require sodium carbonate instead, a few can use calcium, magnesium, or strontium carbonate, and I believe there were a few bromides, iodides, and maybe a fluoride which could be made into rocks too, and maybe even a sulphate or two using the sodium carbonate or something else. I do know people who use both the crack and White Tornado processes on codeine hydrochloride and phosphate, but I wonder why -- I used the ammonia, ether &c process to freebase diacetyldihydromorphine, codeine, and DHC a couple of times, but like smoking opium, I figured it was wasteful and opted for other routes of administration. The results from trying hydrocodone were unclear, and it is much more straightforward to deal with a hydrochloride salt than a bitartrate for this kind of process, it seems.

Coming back on the other end, caffeine especially and certainly anything with theophylline and theobromine in it too is going to increase stomach acid production, so there can be various reasons to counteract that. I used to get going in the beginning of the day with a caffeine tablet, two Ritalin tablets, several pieces of a Hershey bar, and two Rolaids and had good results.
 
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Phobos

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Wondering if anyone has experienced sexual dysfunction using dexamphetamine and baking soda together? Previously no problems until the baking soda was added in. If so what would the reason be?
Appreciate your feedback..

Baking soda modifies the PH in the digestive tract and the Dexamphetamine will dissolve faster and also be absorbed faster and with a slightly higher bioavailability.
It is similar to snorting it, but with a small delay before the start of onset.
ED is most likely being caused by the Dexamphetamine effects being too strong.

To avoid, just reduce the dose of Dexamphetamine.... :cautious:
Nitric oxide supplements and strong doses of vitamin B complex could help with the vasoconstriction that is likely the direct cause of ED.
 

Nicomorphinist

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Baking soda modifies the PH in the digestive tract and the Dexamphetamine will dissolve faster and also be absorbed faster and with a slightly higher bioavailability.
It is similar to snorting it, but with a small delay before the start of onset.
ED is most likely being caused by the Dexamphetamine effects being too strong.

To avoid, just reduce the dose of Dexamphetamine.... :cautious:
Nitric oxide supplements and strong doses of vitamin B complex could help with the vasoconstriction that is likely the direct cause of ED.

With the extra vasoconstriction, do folks have any extra nausea? There is a thread about nausea and vomiting from crack which discusses what happens in that case.
 

Phobos

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Taking recreational doses of racemic Amphetamines orally gives me some stomach discomfort but no nausea.
I seem to have a very hard time to have nausea anyway..
 
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